公开(公告)号：EP3954380A1

公开(公告)日：2022-02-16

申请号：EP20787816.6

申请日：2020-04-08

申请人： Beijing Wehand-Bio Pharmaceutical Co., Ltd ,  Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College

发明人： LIU, Yuling ,  LIAO, Hengfeng ,  GAO, Yue ,  DONG, Wujun ,  LIU, Zhihua ,  WANG, Bangyuan ,  ZHANG, Yun ,  FENG, Yu ,  ZHOU, Junzhuo ,  LIU, Lu ,  YE, Jun ,  YANG, Yanfang ,  XIA, Xuejun

IPC分类号： A61K36/539 ,  A61K9/107 ,  A61P35/00

摘要： A flavonoid polyphenol drug self-emulsifying composition based on a flavonoid polyphenol drug-phospholipid complex being used as an intermediate, the composition comprising a flavonoid polyphenol drug-phospholipid complex, an oil phase, an emulsifier and a co-emulsifier, the flavonoid polyphenol drug comprising one or more selected from baicalein, proanthocyanidin, quercetin, curcumin and resveratrol. The described self-emulsifying composition has the beneficial effects of good stability, a high amount of drug loading, high bioavailability, and so on.