专利检索 ap:("Biophore India Pharmaceuticals Pvt. Ltd." OR "Pullagurla, Manik Reddy" OR "Rangisetty, Jagadeesh Babu") AND inv:"PITTA, Bhaskar Reddy" 第 1 页

1.

发明公开
PROCESS FOR THE PREPARATION OF 2,2',2''-(10-((2R,3S)-1,3,4-TRIHYDROXY BUTAN-2-YL)-1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIYL) TRIACETIC ACID AND ITS COMPLEXES 审中-公开

公开(公告)号：EP3820853A1

公开(公告)日：2021-05-19

申请号：EP19833651.3

申请日：2019-07-10

申请人： Biophore India Pharmaceuticals Pvt. Ltd. , Pullagurla, Manik Reddy , Rangisetty, Jagadeesh Babu

发明人： PITTA, Bhaskar Reddy , PULLAGURLA, Manik Reddy , RANGISETTY, Jagadeesh Babu

IPC分类号： C07D257/00 , A61K49/10 , C07F5/00

2.

发明公开
PROCESS FOR THE PREPARATION OF 2,2',2''-(10-((2R,3S)-1,3,4-TRIHYDROXY BUTAN-2-YL)-1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIYL) TRIACETIC ACID AND ITS COMPLEXES 审中-公开

公开(公告)号：EP4083026A1

公开(公告)日：2022-11-02

申请号：EP22177978.8

申请日：2019-07-10

申请人： Biophore India Pharmaceuticals Pvt. Ltd.

发明人： PITTA, Bhaskar Reddy , PULLAGURLA, Manik Reddy , RANGISETTY, Jagadeesh Babu

IPC分类号： C07D257/02 , A61K49/10 , C07F5/00

摘要： The present invention relates to an improved process for the preparation of 2,2',2"-(10-((2R,3S)-1,3,4-trihydroxy butan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid, gadolinium (III) with iron metal content less than 5 ppm and free gadolinium content less than 10 ppm , which is represented by the formula (1). The present invention further relates to an improved process for the preparation of calcium complex of 10-(2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclo decane-1,4,7-triacetic acid known as Calcobutrol (1a) and its sodium salt of formula (1b) with purity greater than 98.0 %.

3.

发明公开
AN IMPROVED PROCESS FOR THE PREPARATION OF AGOMELATINE POLYMORPHIC FORM-1 审中-公开
标题翻译： VERBESSERTES VERFAHREN ZUR HERSTELLUNG VONMOLYBDÄN-SUCCINIMIDKOMPLEXEN VON POLYMORPHER AGOMELATIN FORM-1

公开(公告)号：EP3119743A2

公开(公告)日：2017-01-25

申请号：EP14886181.8

申请日：2014-12-29

申请人： Biophore India Pharmaceuticals Pvt. Ltd.

发明人： PULLAGURLA, Manik Reddy , RANGISETTY, Jagadeesh Babu , NANDAKUMAR, Mecheril Valsan , PITTA, Bhaskar Reddy

IPC分类号： C07C233/18

CPC分类号： C07C231/24 , C07B2200/13 , C07C233/18

摘要： The invention provides a process for preparation of polymorphic form I of Agomelatine comprising dissolving Agomelatine in a water miscible organic solvent to obtain Agomelatine solution (solution A), preparing a solution of water miscible organic solvent and water (solution B) and cooling to below 0 ºC, adding solution A to solution B at below 0 ºC and precipitating Agomelatine polymorphic Form 1.

摘要翻译： 本发明提供了一种制备阿格美拉定的多晶型I的方法，其包括将阿莫美林溶解在水混溶性有机溶剂中以获得阿维拉平溶液（溶液A），制备水混溶性有机溶剂和水（溶液B）的溶液并冷却至低于0 ºC，在低于0℃的溶液B中加入溶液A，并沉淀出Agomelatine多晶型物1。

4.

发明公开
SOLID FORMS OF 1-{3-[3-(4-CHLOROPHENYL) PROPOXY] PROPYL} PIPERIDINE HYDROCHLORIDE AND PROCESS FOR THE PREPARATION THEREOF 审中-公开

公开(公告)号：EP4457219A1

公开(公告)日：2024-11-06

申请号：EP22915342.4

申请日：2022-12-29

申请人： Biophore India Pharmaceuticals Pvt. Ltd.

发明人： PULLAGURLA, Manik Reddy , KOTHAKONDA, Kiran Kumar , PITTA, Bhaskar Reddy , BOGE, Rajesham , RANGISETTY, Jagadeesh Babu

IPC分类号： C07D295/088

5.

发明公开
NOVEL PROCESS FOR THE PREPARATION OF GADOLINIUM COMPLEX OF (4S)-4-(4-ETHOXYBENZYL)-3,6,9-TRIS(CARBOXYLATOMETHYL)-3,6,9- TRIAZAUNDECANEDIOIC ACID DISODIUM (GADOXETATE DISODIUM) 审中-公开

公开(公告)号：EP3464237A1

公开(公告)日：2019-04-10

申请号：EP17806041.4

申请日：2017-05-30

申请人： Biophore India Pharmaceuticals Pvt. Ltd.

发明人： PULLAGURLA, Manik Reddy , PITTA, Bhaskar Reddy , NAMANI, Suresh Babu , RANGISETTY, Jagadeesh Babu

IPC分类号： C07C229/16 , C07F5/00