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公开(公告)号：EP3995079A1
公开(公告)日：2022-05-11
申请号：EP21206987.6
申请日：2021-11-08
发明人： NAKAR, Elad , BENAROYA, Yoav
摘要： An apparatus includes a shaft, configured for insertion into a body of a subject, and an expandable element coupled to a distal end of the shaft. The expandable element includes multiple electrodes arranged in a hexagonal grid when the expandable element is expanded. Other embodiments are also described.
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公开(公告)号：EP3854305A1
公开(公告)日：2021-07-28
申请号：EP21152433.5
申请日：2021-01-20
摘要： In one embodiment, a medical system includes respective electrodes for application to a body of a subject and to output a set of respective activation signals in response to electrical activity of a heart of the subject captured over a sequence of heartbeat intervals, and a processor to classify a first heartbeat interval of the set of activation signals as a first morphological template, compute a measure of similarity between a second heartbeat interval of the set of activation signals and the first morphological template, group the second heartbeat interval of the set of activation signals in a first morphological group with the first morphological template responsively to the measure exceeding a predefined threshold, and classify the second heartbeat interval of the set of activation signals as a second morphological template responsively to the measure not exceeding the predefined threshold, and repeat the above, mutatis mutandis, for subsequent heartbeat intervals.
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公开(公告)号：EP3821808A1
公开(公告)日：2021-05-19
申请号：EP20207557.8
申请日：2020-11-13
发明人： RAVUNA, Eliyahu , KADOSHI, Yaron , ITAH, Refael , NAKAR, Elad , ALROY, Michal
IPC分类号： A61B5/349
摘要： Methods, apparatus, and systems for medical procedures are disclosed herein and include detecting points of an intra-cardiac area that exhibits abnormal activations, such as local abnormal ventricular activations (LAVAs). Points that exhibit such abnormal activations may be referred to as seed points that are identified during a first step of the process disclosed herein. The seed points may be identified using one or more inputs such as unipolar and bipolar mapping channels, body surface ECGs, past activations, neighboring points and the like during the first step which prioritizes high specificity over sensitivity. During a second step which prioritizes high sensitivity, electrical activations of neighboring points near the seed points are analyzed to determine if the activations are similar (e.g., have a similar time) as the abnormal activations corresponding to the corresponding seed points.
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公开(公告)号：EP3281581A1
公开(公告)日：2018-02-14
申请号：EP17185784.0
申请日：2017-08-10
发明人： BOTZER, Lior , BAR-TAL, Meir , NAKAR, Elad
IPC分类号： A61B5/0456 , A61B5/042 , A61B5/00
CPC分类号： A61B5/04012 , A61B5/0422 , A61B5/0456 , A61B5/6852 , A61B5/6869 , A61B5/7239 , A61B5/743 , A61B2505/05
摘要： A method, including receiving a bipolar signal from a pair of electrodes in proximity to a myocardium of a human subject and receiving a unipolar signal from a selected one of the pair of electrodes. The method further includes computing a local unipolar minimum derivative of the unipolar signal, and a time of occurrence of the unipolar minimum derivative. The method also includes computing a bipolar derivative of the bipolar signal, evaluating a ratio of the bipolar derivative to the local unipolar minimum derivative, and when the ratio is greater than a preset threshold ratio value, identifying the time of occurrence as a time of activation of the myocardium.
摘要翻译： 一种方法，包括接收来自人类受试者心肌附近的一对电极的双极信号，并从该对电极中选定的一个接收单极信号。 该方法还包括计算单极性信号的局部单极性最小导数和单极性最小导数的出现时间。 该方法还包括计算双极性信号的双极性导数，评估双极性导数与局部单极性最小导数之比，并且当该比率大于预设的阈值比值时，将发生时间标识为激活时间 的心肌。
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公开(公告)号：EP4327746A3
公开(公告)日：2024-05-29
申请号：EP24150903.3
申请日：2020-11-13
发明人： RAVUNA, Eliyahu , KADOSHI, Yaron , ITAH, Refael , NAKAR, Elad , ALROY, Michal
CPC分类号： A61B5/349 , A61B5/7264 , A61B5/7203 , G16H40/63 , G16H40/67 , G16H20/40 , G16H30/20 , G16H50/70
摘要： Methods, apparatus, and systems for medical procedures are disclosed herein and include detecting points of an intra-cardiac area that exhibits abnormal activations, such as local abnormal ventricular activations (LAVAs). Points that exhibit such abnormal activations may be referred to as seed points that are identified during a first step of the process disclosed herein. The seed points may be identified using one or more inputs such as unipolar and bipolar mapping channels, body surface ECGs, past activations, neighboring points and the like during the first step which prioritizes high specificity over sensitivity. During a second step which prioritizes high sensitivity, electrical activations of neighboring points near the seed points are analyzed to determine if the activations are similar (e.g., have a similar time) as the abnormal activations corresponding to the corresponding seed points.
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公开(公告)号：EP4042933A1
公开(公告)日：2022-08-17
申请号：EP22162146.9
申请日：2017-08-10
发明人： BOTZER, Lior , BAR-TAL, Meir , NAKAR, Elad
摘要： A computer-implemented method for identifying times of activation of the myocardium. The method includes receiving a bipolar signal from a pair of electrodes in proximity to a myocardium of a human subject; receiving a unipolar signal from a selected one of the pair of electrodes; pre-processing the bipolar signal and the unipolar signal, wherein pre-processing comprises removing baseline wander and applying a low pass filter; extracting features for each of a plurality of candidate annotations; eliminating candidate annotations based on a subset of the extracted features; discarding one candidate annotation from any pairs of candidate annotations which arise from a same time of activation; computing a score for each candidate annotation based on the extracted features; and identifying candidate annotations for which the score is greater than a score threshold as times of activation of the myocardium.
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7.发明公开
公开(公告)号：EP4018931A1
公开(公告)日：2022-06-29
申请号：EP21216283.8
申请日：2021-12-21
发明人： ITAH, Refael , KATZ, Natan Sharon , KADOSHI, Yaron , HAYAM, Gal , NAKAR, Elad , BAR-ON, Tal Haim , RAVUNA, Eliyahu , BOTZER, Lior , BENAROYA, Yoav , CORTEZ-DIAZ, Nuno Miguel Rocha
摘要： A method includes receiving a bipolar signal sensed by a pair of electrodes at a location in a heart of a patient. One or more electrocardiogram (ECG) signals are received, sensed by body-surface electrodes attached to the patient. Two or more successive QRS complexes are identified in the bipolar signal. One or more activations are detected in the bipolar signal, which occur within a window-of-interest that begins at least a given time with respect to the identified QRS complexes. The detected activations are checked whether they are late potentials, by verifying whether (i) the activations do not coincide with a predefined event observed in the ECG signals, and (ii) the activations are repeatable in the successive QRS complexes. In response to deciding that at least one of the detected activations is a late potential, the latest of the at least one of the late potentials is visualized to a user.
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公开(公告)号：EP3960083A1
公开(公告)日：2022-03-02
申请号：EP21192941.9
申请日：2021-08-25
摘要： A method that is executed by a determination engine is provided. The method includes receiving one or more pairs of heart beats, generating a model based on the one or more pairs of heart beats, and determining whether two given heart beats are part of a same arrythmia to produce a similarity result for algorithmic input.
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公开(公告)号：EP3937181A1
公开(公告)日：2022-01-12
申请号：EP21183847.9
申请日：2021-07-06
发明人： RAVUNA, Eliyahu , AMIT, Matitiyahu , YARNITSKI, Jonathan , ITAH, Refael , TSOREF, Liat , DORON, Itai , SHALGI, Avi , ZIV-ARI, Morris , BOTZER, Lior , GOLDBERG, Stanislav , NAKAR, Elad , COHEN, Assaf , LEV, Iddo
IPC分类号： G16H20/40
摘要： A method and apparatus of aiding a physician in locating an area to perform an ablation on patients with atrial fibrillation (AFIB) includes receiving data at a machine, from at least one device, the data including information relating to a desired location for performing an ablation, generating, by the machine, an optimal location for performing the ablation based upon the data and inputs, and providing an optimal set of ablation parameters for performing the ablation at the location output by the model, or at a location specified by the physician.
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公开(公告)号：EP3281580A1
公开(公告)日：2018-02-14
申请号：EP17185772.5
申请日：2017-08-10
发明人： BOTZER, Lior , BAR-TAL, Meir , NAKAR, Elad , SALOMON, Noga
IPC分类号： A61B5/0456 , A61B5/042 , A61B5/00
CPC分类号： A61B5/04012 , A61B5/0422 , A61B5/0456 , A61B5/6852 , A61B5/6869 , A61B5/7264 , A61B5/743 , A61B2505/05
摘要： A method, including receiving a bipolar signal from a pair of electrodes in proximity to a myocardium of a human subject, and receiving a unipolar signal from a selected one of the pair of electrodes. The method further includes delineating a window of interest (WOI) for the unipolar and bipolar signals, within the WOI computing local unipolar minimum derivatives of the unipolar signal, and times of occurrence of the local unipolar minimum derivatives, and within the WOI computing bipolar derivatives of the bipolar signal at the times of occurrence. The method also includes evaluating ratios of the bipolar derivatives to the local unipolar minimum derivatives, and when the ratios are greater than a preset threshold ratio value, assigning the times of occurrence as times of activation of the myocardium, counting a number of the times of activation; and classifying the unipolar signal according to the number.
摘要翻译： 一种方法，包括接收来自人类受试者心肌附近的一对电极的双极信号，并从该对电极中选定的一个接收单极信号。 该方法还包括在单极性信号的WOI计算局部单极性最小导数内以及局部单极性最小导数的出现时间内以及在WOI计算双极性导数内为单极性和双极性信号描绘感兴趣窗口（WOI） 的双极性信号在发生时。 该方法还包括评估双极导数与局部单极最小导数的比率，并且当比率大于预设的阈值比值时，将发生次数指定为心肌激活的次数， 激活; 并根据该号码对单极性信号进行分类。
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