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公开(公告)号:EP0638077A1
公开(公告)日:1995-02-15
申请号:EP93909073.0
申请日:1993-04-21
申请人: Chiroscience Limited
CPC分类号: C07D307/935 , C07C35/06 , C12P17/04 , C12P41/004
摘要: An optically-purified enantiomer of the lactone 4-hydroxy-2-oxabicyclo-[3.3.0]oct-7-en-3-one or an acylate thereof can be obtained by biotransformation. It is a useful synthon in the preparation of an enantiomer of 3-hydroxymethyl-2-hydroxycyclopentene that can be used to prepare carbocyclic nucleosides as a desired enantiomer.