专利检索 ap:("Crystal Pharma, S.A.U.") AND inv:"PÉREZ ENCABO, Alfonso" 第 1 页

1.

发明公开
PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZO[B]THIOPHENE COMPOUNDS 审中-公开
标题翻译： ZZHENCHENPRODUKTEFÜRDIE HERSTELLUNG VON BENZO [B] THIOPHENVERBINDUNGEN

公开(公告)号：EP3150591A1

公开(公告)日：2017-04-05

申请号：EP15382479.2

申请日：2015-10-02

申请人： Crystal Pharma S.A.U

发明人： PÉREZ ENCABO, Alfonso , TURIEL HERNANDEZ, José Angel , FERNÁNDEZ SAINZ, Yolanda , LORENTE BONDE-LARSEN, Antonio

IPC分类号： C07D401/12 , C07D241/12 , C07D417/14

CPC分类号： C07D417/14 , C07D241/12 , C07D401/12

摘要： A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.

摘要翻译： 一种制备式（I）化合物或其盐或溶剂化物的方法，包括布匹匹哌唑，该方法包括使式（II）或（III）化合物环化，或其盐或溶剂化物。本发明还涉及所述方法的中间体。

2.

发明公开
SYNTHESIS OF ABIRATERONE AND RELATED COMPOUNDS 审中-公开
标题翻译：阿比特龙及相关化合物的合成

公开(公告)号：EP2794633A2

公开(公告)日：2014-10-29

申请号：EP12808819.2

申请日：2012-12-20

申请人： Crystal Pharma S.A.U

发明人： PÉREZ ENCABO, Alfonso , TURIEL HERNANDEZ, José Angel , GALLO NIETO, Francisco Javier , LORENTE BONDE-LARSEN, Antonio , SANDOVAL RODRÍGUEZ, Celso Miguel

IPC分类号： C07J41/00 , C07J43/00 , C07J75/00

CPC分类号： C07J41/0005 , C07J1/0011 , C07J13/005 , C07J43/003 , C07J51/00

摘要： The present invention relates to processesfor obtaining abirateroneand derivatives thereof, such as abiraterone acetate, by means of a Suzuki coupling through a steroid borate of general formula (IV) or a C-C coupling through a steroid hydrazone of general formula (II), as well as to intermediates useful in said processes.

3.

发明授权
PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZO[B]THIOPHENE COMPOUNDS 有权

公开(公告)号：EP3356342B1

公开(公告)日：2020-01-08

申请号：EP16774688.2

申请日：2016-09-30

申请人： Crystal Pharma, S.A.U.

发明人： PÉREZ ENCABO, Alfonso , TURIEL HERNANDEZ, José Angel , FERNÁNDEZ SAINZ, Yolanda , LORENTE BONDE-LARSEN, Antonio

IPC分类号： C07D401/12 , C07D241/12 , C07D417/14

4.

发明公开
PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZO[B]THIOPHENE COMPOUNDS 审中-公开

公开(公告)号：EP3356342A1

公开(公告)日：2018-08-08

申请号：EP16774688.2

申请日：2016-09-30

申请人： Crystal Pharma, S.A.U.

发明人： PÉREZ ENCABO, Alfonso , TURIEL HERNANDEZ, José Angel , FERNÁNDEZ SAINZ, Yolanda , LORENTE BONDE-LARSEN, Antonio

IPC分类号： C07D401/12 , C07D241/12 , C07D417/14

摘要： A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.