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公开(公告)号：EP3193884A4
公开(公告)日：2018-06-20
申请号：EP15842970
申请日：2015-08-12
申请人： EPIZYME INC
IPC分类号： A61K31/7076 , A61K31/7064 , A61K31/7068 , A61K31/708 , A61K45/06 , A61P35/00
CPC分类号： A61K31/52 , A61K31/519 , A61K2300/00
摘要： The disclosure relates to combinations comprising inhibitors of human histone methyltransferase DOT1L and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
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公开(公告)号：EP3180010A4
公开(公告)日：2018-06-20
申请号：EP15832175
申请日：2015-08-12
申请人： EPIZYME INC , CELGENE CORP
发明人： KLAUS CHRISTINE , RAIMONDI MARIA ALEJANDRA , DAIGLE SCOTT RICHARD , POLLOCK ROY MACFARLANE , CHOPRA VIVEK
IPC分类号： A61K31/7076 , A61K31/7064 , A61K31/7068 , A61K31/708 , A61K45/06 , A61P35/00
CPC分类号： A61K31/7064 , A61K31/135 , A61K31/136 , A61K31/4045 , A61K31/4745 , A61K31/519 , A61K31/5377 , A61K31/704 , A61K31/706 , A61K31/7068 , A61K31/7076 , A61K45/06 , A61P35/00 , A61K2300/00
摘要： The disclosure relates to combinations comprising inhibitors of human histone methyltransferase DOT1L and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
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公开(公告)号：EP2968343A4
公开(公告)日：2016-11-02
申请号：EP14769036
申请日：2014-03-14
申请人： EPIZYME INC
IPC分类号： A61K31/52 , A61K31/136 , A61K31/4745 , A61K31/551 , A61K31/704 , A61K31/706 , A61K31/7064 , A61K31/7068 , A61K31/7076 , A61P35/00 , C07D473/34 , C07D487/04 , C07H19/044 , C07H19/16
CPC分类号： A61K31/7076 , A61K31/136 , A61K31/4745 , A61K31/551 , A61K31/704 , A61K31/706 , A61K31/7064 , A61K31/7068 , C07H19/044 , C07H19/16 , A61K2300/00
摘要： The present invention relates to compositions comprising inhibitors of human histone methyltransferase DOT1L and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
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