公开(公告)号：EP4198025A1

公开(公告)日：2023-06-21

申请号：EP21214773.0

申请日：2021-12-15

申请人： Eberhard Karls Universität Tübingen Medizinische Fakultät

发明人： Schütz, Monika ,  Renschler, Fabian ,  Schweers, Jonas Malte ,  Autenrieth, Ingo ,  Poso, Antti ,  Kronenberger, Thales ,  Kurki, Milla ,  Turhanen, Petri ,  Leini, Renne ,  Schmidberger, Gregor

IPC分类号： C07D235/14 ,  C07D403/12 ,  A61K31/4184 ,  A61P31/04

摘要： The invention relates to a novel compound for the treatment and prophylaxis of a disease, especially a bacterial infectious disease, for reducing pathogen virulence and promoting host-induced clearance of infection and/or sensitizing bacteria to antibiotic treatment, a method for preparing said compound, a pharmaceutical composition comprising said compound, and to a method for the treatment and/or prophylaxis of a disease, preferably a bacterial infectious disease.

公开(公告)号：EP4197596A1

公开(公告)日：2023-06-21

申请号：EP21214755.7

申请日：2021-12-15

申请人： Eberhard Karls Universität Tübingen Medizinische Fakultät ,  Universiteit Antwerpen

发明人： Schütz, Monika ,  Renschler, Fabian ,  Schweers, Jonas Malte ,  Autenrieth, Ingo ,  Poso, Antti ,  Kronenberger, Thales ,  Augustyns, Koen ,  Kurki, Milla ,  Cantini, Niccolo ,  Valembois, Sophie

IPC分类号： A61P31/04 ,  C07D233/90

摘要： The invention relates to a novel compound for the treatment and prophylaxis of a disease, especially a bacterial infectious disease, for reducing pathogen virulence and promoting host-induced clearance of infection and/or sensitizing bacteria to antibiotic treatment, a method for preparing said compound, a pharmaceutical composition comprising said compound, and to a method for the treatment and/or prophylaxis of a disease, preferably a bacterial infectious disease.