Method for diagnosing cancer using cancer-associated deletion gene marker
    1.
    发明公开
    Method for diagnosing cancer using cancer-associated deletion gene marker 审中-公开
    Verfahren zur Krebsdiagnose mittels Genmarkerfürkrebsassoziierte Deletionen

    公开(公告)号:EP1852513A2

    公开(公告)日:2007-11-07

    申请号:EP07007420.8

    申请日:2007-04-11

    IPC分类号: C12Q1/68

    摘要: It is an object of the present invention to provide a novel method for diagnosing cancer by discovering a cancer-associated gene which could not be detected by a conventional technique, and detecting deletion, mutation, or an abnormal expression level of such cancer-associated gene. The present invention pmvides a method for diagnosing cancer which comprises a step of detecting deletion of the GMDS, ANKRD15, TEK, or EBI2 gene in a test sample by using DNA containing all or part of said gene.

    摘要翻译: 本发明的目的是提供一种通过发现通过常规技术无法检测到的癌症相关基因并检测这种癌症相关基因的缺失,突变或异常表达水平来诊断癌症的新方法 。 本发明提供了一种用于诊断癌症的方法,其包括通过使用含有全部或部分所述基因的DNA检测测试样品中GMDS,ANKRD15,TEK或EBI2基因的缺失的步骤。

    Method for detecting abnormal spots of nucleic acid microarray
    4.
    发明公开
    Method for detecting abnormal spots of nucleic acid microarray 有权
    福尔法罕zur Erkennung异常Punkte einesNukleinsäuremikroarrays

    公开(公告)号:EP2261370A1

    公开(公告)日:2010-12-15

    申请号:EP10164051.4

    申请日:2010-05-27

    IPC分类号: C12Q1/68 G06F19/00

    摘要: A method carries out a nucleic acid analysis using a nucleic acid microarray. A probe nucleic acid including a probe sequence (a') complementary to a target sequence (a) and a sequence (b') which is different from the probe sequence (a') is immobilized on the nucleic acid microarray. The method includes hybridizing the nucleic acid microarray and a labeled abnormality detecting nucleic acid (B) containing a sequence (b) which can be bound to the sequence (b'), obtaining a labeled amount value (Fc1) of the labeled abnormality detecting nucleic acid (B) from a spot (X1), and determining, based on the measured labeled amount value (Fc1), as to whether or not the spot (X1) is an abnormal spot unsuitable for detecting the target nucleic acid.

    摘要翻译: 一种方法使用核酸微阵列进行核酸分析。 包含与靶序列(a)互补的探针序列(a')和不同于探针序列(a')的序列(b')的探针核酸被固定在核酸微阵列上。 该方法包括将核酸微阵列和含有可与序列(b')结合的序列(b)的标记异常检测核酸(B)杂交,得到标记的异常检测核酸的标记量值(Fc1) 根据测定的标记量值(Fc1),确定斑点(X1)是否是不适于检测靶核酸的异常斑点。

    Method for detecting cancer and method for suppressing cancer
    5.
    发明公开
    Method for detecting cancer and method for suppressing cancer 有权
    一种用于检测甲状腺未分化癌的方法,以及用于它的抑制方法

    公开(公告)号:EP1837405A2

    公开(公告)日:2007-09-26

    申请号:EP07005922.5

    申请日:2007-03-22

    IPC分类号: C12Q1/68

    摘要: An object of the present invention is to provide a method for detecting cancer through identification of genes exhibiting characteristic behavior in the cases of cancer such as anaplastic thyroid cancer. The present invention provides a method for detecting cancer which comprises detecting canceration of a specimen using the amplification of a gene of the p12 region of chromosome 8 in the specimen as an indicator.

    摘要翻译: 本发明的一个目的是提供一种用于通过基因表现出癌症的箱子特征行为的识别检测癌症的方法:如甲状腺未分化癌。 本发明提供用于检测癌症,其包括使用8号染色体的样品中的P12区域的基因的扩增为指标检测样本的癌化的方法。

    Method for detecting oral squamous-cell carcinoma and method for suppressing the same
    9.
    发明公开
    Method for detecting oral squamous-cell carcinoma and method for suppressing the same 审中-公开
    用于检测口腔鳞状和方法用于抑制相同的方法

    公开(公告)号:EP1997911A2

    公开(公告)日:2008-12-03

    申请号:EP08009943.5

    申请日:2008-05-30

    IPC分类号: C12Q1/68

    摘要: An object of the present invention is to provide a method for detecting cancer through identification of genes exhibiting characteristic behavior in the cases of cancer such as oral squamous-cell carcinoma, and a cell growth inhibitor. The present invention provides a method for detecting cancer, which comprises detecting canceration including malignancy of a specimen through detection of at least one alteration of a gene existing in a chromosomal region 1q21, 2q24.1-q24.2, 3p13, 7p11.2, 10p12.1, 11p15.4, 11p15.2, 11p13.3, 11q22, 11q23.3, 12p13, 12q24.31, 13q33.3-q34, 12q24.1, 19q13, or 22q12.1 in the specimen.

    摘要翻译: 本发明的一个目的是提供一种用于通过基因表现出癌症的箱子特征行为的识别检测癌症的方法:如口腔鳞状细胞癌,和细胞生长抑制剂。 本发明提供了一种用于检测癌症的方法,其包括通过检测存在于染色体区域1q21的基因的至少一个改变的检测癌变包含检体恶性肿瘤,2q24.1-q24.2,3p13,7p11.2, 10p12.1,11p15.4,11p15.2,11p13.3,11q22,11q23.3,12p13,12q24.31,13q33.3-Q34,12q24.1,19q13,或22q12.1中的标本。

    Method for detecting multiple myeloma and method for inhibiting the same
    10.
    发明公开
    Method for detecting multiple myeloma and method for inhibiting the same 审中-公开
    Verfahren zur Erkennung mehrerer Myelome und Verfahren zu deren Hemmung

    公开(公告)号:EP1905845A2

    公开(公告)日:2008-04-02

    申请号:EP07018522.8

    申请日:2007-09-20

    CPC分类号: C12Q1/6886 C12Q2600/158

    摘要: It is an object of the present invention to identify a gene that relates to exhibition of behavior peculiar to cancer such as multiple myeloma to provide a method for detecting cancer and a cell-growth inhibitor. The present invention provides a method for detecting cancer which comprises detecting and/or typing tumorigenesis of a specimen by employing gene amplification in the chromosome 11 q23 region of the specimen as an indicator.

    摘要翻译: 本发明的目的是鉴定涉及癌症如多发性骨髓瘤特有的行为的表现的基因,以提供用于检测癌症的方法和细胞生长抑制剂。 本发明提供了一种检测癌症的方法,其包括通过在样本的染色体11q23区域中进行基因扩增作为指标检测和/或分类标本的肿瘤发生。