公开(公告)号：EP2246299A1

公开(公告)日：2010-11-03

申请号：EP08710958.3

申请日：2008-02-01

申请人： GL Sciences Incorporated

发明人： MIYAZAKI, Shota ,  TERASHIMA, Hiroyuki ,  NYUDO, Masahiko ,  OHIRA, Masayoshi ,  MORISATO, Kei ,  FURUNO, Masahiro

IPC分类号： C01B33/12 ,  B01D15/08 ,  B01J20/10 ,  B01J20/28 ,  B01J20/32 ,  G01N30/88

CPC分类号： B01D15/22 ,  B01D15/20 ,  B01J20/103 ,  B01J20/28042 ,  B01J20/283 ,  B01J20/3257 ,  B01J2220/54 ,  B01J2220/82 ,  B01J2220/825 ,  G01N30/50 ,  G01N30/6052 ,  G01N2030/528

摘要： To use a monolithic silica body in chromatography with a HPLC column or a GC column and to simplify the use thereof as a separation medium, it is intended to provide a method of cladding a main body of a monolithic adsorbent or separating agent with glass so as to protect the outer surface, and to provide a separation medium prepared by the method. To this end, a monolithic silica body alone is formed by molding, and the molding is coated with a glass body; and then the glass body and the monolithic silica body are fused and integrated at the melting temperature of the glass body at an appropriate pressure. The surface of the resulting monolithic silica body clad with glass is strongly protected by the glass, and the homogeneity of the interior of the monolithic silica body is maintained, and thus uniform flow of a sample solution ensures analytical accuracy.

摘要翻译： 为了在使用HPLC柱或GC色谱柱的色谱法中使用整体式二氧化硅体，并且为了简化其作为分离介质的用途，旨在提供一种用玻璃包覆整体式吸附剂或分离剂的主体的方法，以便 以保护外表面，并提供通过该方法制备的分离介质。 为此，单独的整体式二氧化硅体通过成型而形成，成型用玻璃体涂布; 然后玻璃体和整体式二氧化硅体在玻璃体的熔融温度下以适当的压力熔融并整合。 用玻璃覆盖的所得整体二氧化硅体的表面被玻璃强烈保护，并且保持了整体二氧化硅体内部的均匀性，因此样品溶液的均匀流动确保了分析精度。