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1.发明公开IMIDAZO [1, 2-C]PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS 审中-公开咪唑并[1,2-C]吡啶二酮-2-甲基乙基哌啶盐酸盐
公开(公告)号：EP2176265A1
公开(公告)日：2010-04-21
申请号：EP08774575.8
申请日：2008-07-01
申请人： Glaxo Group Limited
IPC分类号： C07D487/04 , A61K31/519 , A61P3/04 , A61P3/10
CPC分类号： C07D487/04
摘要： This invention relates to imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives and their use as pharmaceuticals.
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公开(公告)号：EP2358713A1
公开(公告)日：2011-08-24
申请号：EP08875373.6
申请日：2008-11-26
申请人： Glaxo Group Limited
IPC分类号： C07D487/04 , A61K31/5025 , A61P3/04 , A61P3/10 , A61P25/00 , A61P25/22 , A61P25/24
CPC分类号： C07D487/04
摘要： This invention, relates to imidazopyridazine substituted piperidine derivatives (I) and their use as orexin antagonists.
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公开(公告)号：EP2358711A1
公开(公告)日：2011-08-24
申请号：EP08875371.0
申请日：2008-11-26
申请人： Glaxo Group Limited
IPC分类号： C07D487/04 , A61K31/4985 , A61P3/00 , A61P25/00
CPC分类号： C07D487/04
摘要： This invention relates to imidazopyrimidine substituted piperidine derivatives of formula (I) and their use as orexin receptor antagonists useful in the treatment of sleep disorders, mood disorders and anxiety related disorders.
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公开(公告)号：EP2176258A1
公开(公告)日：2010-04-21
申请号：EP08785891.6
申请日：2008-07-01
申请人： Glaxo Group Limited
IPC分类号： C07D471/04 , A61K31/437 , A61P3/00 , A61P7/00 , A61P25/00
CPC分类号： C07D471/04
摘要： This invention relates to imidazo[1,2-alpha]pyridin-2-ylmethyl substituted piperidine derivatives of formula (I) and their use as pharmaceuticals, in the treatment of obesity and diabetes.
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公开(公告)号：EP2358712A1
公开(公告)日：2011-08-24
申请号：EP08875372.8
申请日：2008-11-26
申请人： Glaxo Group Limited
IPC分类号： C07D487/04 , A61K31/519 , A61P3/00 , A61P25/00
CPC分类号： C07D487/04
摘要： This invention relates to imidazopyrimidine substituted piperidine derivatives of formula (I) and their use as orexin receptor antagonists useful in the treatment of sleep disorders, mood disorders and anxiety related disorders.
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