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    PLASTER STRUCTURE FOR IONTOPHORESIS
    2.
    发明公开
    PLASTER STRUCTURE FOR IONTOPHORESIS 失效
    IOPOPHORESE PFLASTER

    公开(公告)号：EP0846473A1

    公开(公告)日：1998-06-10

    申请号：EP95928026.4

    申请日：1995-08-14

    申请人： HISAMITSU PHARMACEUTICAL CO. INC.

    发明人： HIGO, Naruhito ,  MORI, Kenji ,  NAKAMURA, Katsuhiro

    IPC分类号： A61N1/30

    CPC分类号： A61N1/0448 ,  A61N1/0428 ,  A61N1/303

    摘要： It is an object of this invention to provide a plaster structure for iontophoresis in which a predetermined amount of physiologically active agents initially set can be stably kept or held without any loss until it is applied to a patient, and when the agents are applied to the patient, the predetermined amount of physiologically active agents initially set can be applied stably and continuously to an entire body of the patient and concurrently a mutual action between the physiologically active agents or additive agents and the adhesive agent is prevented, an adhering power of the adhesive agent is kept and it may not be peeled off during its application.
    The plaster structure for iontophoresis is comprised of an electrical conductive medicinal substance storing layer 1 containing the physiologically active agents, a backing layer 2 covering the medicinal substance storing layer 1 and having an electrode 3 installed therein, a protection layer 4 supporting the medicinal substance storing layer 1 and which is non-permeable against the physiologically active agents, an adhesive agent layer 5 comprised of pressure-sensitive adhesive agent with a superior skin adhering characteristic and/or mucous membrane adhering characteristic laminated on the other surface of the protection layer 4, a liner layer 6 laminated on the other surface of the adhesive agent layer 5, and a notch part 7 formed in the protection layer 4.

    摘要翻译： 本发明的目的是提供一种用于离子电渗疗法的膏药结构，其中初始设定的预定量的生理活性剂可以稳定地保持或保持，直到其施用于患者，并且当将药剂施用于 患者，可以将初始设定的预定量的生理活性剂稳定且持续地施用于患者的整个身体，同时可以防止生理活性剂或添加剂与粘合剂之间的相互作用，粘合剂的粘附力 代理商被保留，并且在应用期间可能不会剥离。 用于离子电渗的石膏结构由含有生理活性剂的导电药物储存层1，覆盖药物储存层1的背衬层2和安装有电极3的保护层4构成，保护层4支撑药物储存 层1，其对于生理活性剂是不可渗透的，由保护层4的另一表面层压的具有优异的表皮粘附特性和/或粘膜粘附特性​​的压敏粘合剂组成的粘合剂层5， 层叠在粘合剂层5的另一个表面上的衬里层6和形成在保护层4中的凹口部7.图像

    DEVICE FOR IONTOPHORESIS
    5.
    发明公开
    DEVICE FOR IONTOPHORESIS 审中-公开
    IONTOPHORESEGERÄT

    公开(公告)号：EP1163926A1

    公开(公告)日：2001-12-19

    申请号：EP00903965.2

    申请日：2000-02-16

    申请人： HISAMITSU PHARMACEUTICAL CO. INC.

    发明人： INOUE, Kazutaka ,  ADACHI, Hirotoshi ,  MAEDA, Hiroyuki ,  HIGO, Naruhito

    IPC分类号： A61N1/30

    CPC分类号： A61N1/30

    摘要： This is an iontophoresis device being able to determine a conduction state with high accuracy. A voltage comparator (10B) compares an output current signal (18) indicative of a reactive current flowing through a skin or a mucous with a threshold level (SL) pre-adjusted to a voltage value corresponding to a lower limit of the reactive current, thereby detecting the presence or absence of the reactive current. If the output current signal is higher than the threshold level, the voltage comparator generates an output signal (11B) of "H" to indicate to the controlling circuit that the conduction state is normal. If the output current signal is lower than the threshold level, the voltage comparator generates an output signal (11B) of "L" to indicate to the controlling circuit that the conduction state is abnormal.

    摘要翻译： 这是能够以高精度确定导通状态的离子电渗装置。 电压比较器（10B）将指示流过皮肤或粘液的无功电流的输出电流信号（18）与预调节到对应于无功电流的下限的电压值的阈值电平（SL）进行比较， 从而检测无功电流的有无。 如果输出电流信号高于阈值电平，则电压比较器产生“H”的输出信号（11B），以向控制电路指示导通状态正常。 如果输出电流信号低于阈值电平，则电压比较器产生“L”的输出信号（11B），以向控制电路指示导通状态异常。

    PASTING AGENT
    8.
    发明公开
    PASTING AGENT 有权
    KLEBEMITTEL

    公开(公告)号：EP1547589A1

    公开(公告)日：2005-06-29

    申请号：EP03791198.9

    申请日：2003-08-07

    申请人： HISAMITSU PHARMACEUTICAL CO., INC.

    发明人： ITO, Takeshi ,  TATEISHI, Tetsuro ,  HIGO, Naruhito

    IPC分类号： A61K31/221 ,  A61K9/70 ,  A61K47/12 ,  A61K47/32 ,  A61P13/10

    CPC分类号： A61K9/7053 ,  A61K9/7061 ,  A61K9/7076 ,  A61K31/221 ,  A61K47/12 ,  A61K47/32

    摘要： A patch comprising a backing layer and an adhesive layer disposed on the backing layer and compounded with an adhesive agent and oxybutynin and/or a pharmaceutically acceptable salt thereof, wherein the adhesive agent comprises an acrylic polymer substantially free of both carboxyl group and hydroxyl group and a rubber polymer, in which weight ratio of content of the acrylic polymer to content of the rubber polymer is from 1:4 to 1:19.

    摘要翻译： 一种贴剂，其包括背衬层和设置在背衬层上并与粘合剂和奥昔布宁和/或其药学上可接受的盐复合的粘合剂层，其中所述粘合剂包含基本上不含羧基和羟基的丙烯酸聚合物， 橡胶聚合物，其中丙烯酸类聚合物的含量与橡胶聚合物的含量的重量比为1:4至1:19。