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公开(公告)号：EP3013946B1
公开(公告)日：2019-02-06
申请号：EP14733199.5
申请日：2014-06-27
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2.发明公开METHODS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINA OF A SUBJECT 审中-公开表达的目的多核苷酸的一个人的视网膜方法
公开(公告)号：EP3013946A1
公开(公告)日：2016-05-04
申请号：EP14733199.5
申请日：2014-06-27
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Pierre et Marie Curie (Paris 6) , Centre National de la Recherche Scientifique (CNRS)
CPC分类号： A61K48/0075 , A61K9/0048 , A61K31/713 , A61K38/465 , C07K14/4703 , C12N7/00 , C12N15/113 , C12N15/86 , C12N2310/14 , C12N2320/31 , C12N2320/32 , C12N2750/14142 , C12N2750/14143 , C12N2750/14171 , C12Y301/00
摘要： Provided herein are methods for expressing a polynucleotide of interest in the retina of a subject. In particular, a method for expressing a polynucleotide of interest in the retina of a subject comprising the step consisting of injecting into the vitreous an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression is provided.
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公开(公告)号：EP3013946B8
公开(公告)日：2019-04-10
申请号：EP14733199.5
申请日：2014-06-27
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