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公开(公告)号：EP3013946B8
公开(公告)日：2019-04-10
申请号：EP14733199.5
申请日：2014-06-27
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公开(公告)号：EP3013946B1
公开(公告)日：2019-02-06
申请号：EP14733199.5
申请日：2014-06-27
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3.发明授权METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS 有权Basigin激动剂神经退行性疾病的治疗
公开(公告)号：EP2442820B1
公开(公告)日：2015-09-23
申请号：EP10727391.4
申请日：2010-06-18
申请人： INSERM - Institut National de la Santé et de la Recherche Médicale , Centre National de la Recherche Scientifique (CNRS)
CPC分类号： G01N33/5058 , A61K38/52 , G01N33/5023 , G01N2333/70596 , G01N2800/28
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4.发明授权
公开(公告)号：EP2997974B1
公开(公告)日：2018-06-13
申请号：EP15180776.5
申请日：2010-06-18
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , CNRS (Centre National de la Recherche Scientifique)
CPC分类号： G01N33/5058 , A61K38/52 , G01N33/5023 , G01N2333/70596 , G01N2800/28
摘要： The invention relates to compounds which activate the BASIGIN signalling pathway, preferably agonists of BASIGIN, for the treatment of neurodegenerative disorders.
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5.发明公开METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS 有权Basigin激动剂神经退行性疾病的治疗
公开(公告)号：EP2442820A1
公开(公告)日：2012-04-25
申请号：EP10727391.4
申请日：2010-06-18
CPC分类号： G01N33/5058 , A61K38/52 , G01N33/5023 , G01N2333/70596 , G01N2800/28
摘要： The invention relates to compounds which activate the BASIGIN signalling pathway, preferably agonists of BASIGIN, for the treatment of neurodegenerative disorders.
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6.发明公开METHODS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINA OF A SUBJECT 审中-公开表达的目的多核苷酸的一个人的视网膜方法
公开(公告)号：EP3013946A1
公开(公告)日：2016-05-04
申请号：EP14733199.5
申请日：2014-06-27
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Pierre et Marie Curie (Paris 6) , Centre National de la Recherche Scientifique (CNRS)
CPC分类号： A61K48/0075 , A61K9/0048 , A61K31/713 , A61K38/465 , C07K14/4703 , C12N7/00 , C12N15/113 , C12N15/86 , C12N2310/14 , C12N2320/31 , C12N2320/32 , C12N2750/14142 , C12N2750/14143 , C12N2750/14171 , C12Y301/00
摘要： Provided herein are methods for expressing a polynucleotide of interest in the retina of a subject. In particular, a method for expressing a polynucleotide of interest in the retina of a subject comprising the step consisting of injecting into the vitreous an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression is provided.
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7.发明公开METHOD AND PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS 有权方法和药物组合物，使用于治疗神经退行性疾病
公开(公告)号：EP2997974A1
公开(公告)日：2016-03-23
申请号：EP15180776.5
申请日：2010-06-18
申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , CNRS (Centre National de la Recherche Scientifique)
CPC分类号： G01N33/5058 , A61K38/52 , G01N33/5023 , G01N2333/70596 , G01N2800/28
摘要： The invention relates to compounds which activate the BASIGIN signalling pathway, preferably agonists of BASIGIN, for the treatment of neurodegenerative disorders.
摘要翻译： 本发明涉及一种激活Basigin信号传导途径，优选Basigin的激动剂，神经退行性病症的治疗化合物。
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