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公开(公告)号：EP3359565A1
公开(公告)日：2018-08-15
申请号：EP16782018.2
申请日：2016-10-04
发明人： KRAUS, Alexandra , HARTLEPP, Felix , MAHR, Andrea , WEINSCHENK, Toni , WAGNER, Claudia , MAURER, Dominik
CPC分类号： C07K16/2833 , A61K2039/505 , C07K14/4748 , C07K16/18 , C07K2317/21 , C07K2317/32 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/732 , G01N33/53 , G01N33/6854 , G01N2500/04
摘要： The present invention relates to antibodies or fragments thereof binding to human WT1/HLA. In particular, the present invention relates to antibodies or fragments thereof that have combined improved and/or beneficial properties, and are therefore suited for clinical development.
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2.发明公开
公开(公告)号：EP3897698A2
公开(公告)日：2021-10-27
申请号：EP19831680.4
申请日：2019-12-18
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公开(公告)号：EP3853243A1
公开(公告)日：2021-07-28
申请号：EP19773029.4
申请日：2019-09-17
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公开(公告)号：EP3813873A1
公开(公告)日：2021-05-05
申请号：EP19733696.9
申请日：2019-06-19
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公开(公告)号：EP3319985B1
公开(公告)日：2020-10-28
申请号：EP16736073.4
申请日：2016-07-05
发明人： MAHR, Andrea , WEINSCHENK, Toni , SONG, Colette , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
IPC分类号： C07K14/47 , C07K14/635 , A61K39/00
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公开(公告)号：EP3456339A3
公开(公告)日：2019-03-27
申请号：EP18201334.2
申请日：2014-08-04
IPC分类号： A61K38/17 , A61K39/00 , C07K7/06 , C12N5/0783
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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7.发明公开
公开(公告)号：EP3456347A1
公开(公告)日：2019-03-20
申请号：EP18201235.1
申请日：2016-03-24
发明人： MAHR, Andrea , STEVERMANN, Lea , WEINSCHENK, Toni , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：EP3429617A1
公开(公告)日：2019-01-23
申请号：EP17710882.6
申请日：2017-03-14
发明人： MAHR, Andrea , SCHOOR, Oliver , WEINSCHENK, Toni
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9.发明公开
公开(公告)号：EP3341014A1
公开(公告)日：2018-07-04
申请号：EP16762752.0
申请日：2016-08-26
CPC分类号： A61K39/0011 , C07K14/4748 , C07K16/2833 , C12N15/115 , C12N2310/16
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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10.发明公开NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST ESOPHAGEAL CANCER AND OTHER CANCERS 审中-公开用于免疫抑制食管癌和其他癌症的新肽和肽的组合
公开(公告)号：EP3319985A2
公开(公告)日：2018-05-16
申请号：EP16736073.4
申请日：2016-07-05
发明人： MAHR, Andrea , WEINSCHENK, Toni , SONG, Colette , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
IPC分类号： C07K14/47 , C07K14/635 , A61K39/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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