公开(公告)号：EP2144998A1

公开(公告)日：2010-01-20

申请号：EP08826570.7

申请日：2008-04-04

申请人： Inviragen, INC.

发明人： STINCHCOMB, Dan T. ,  OSORIO, Jorge E. ,  WIGGAN, O'Neil

IPC分类号： C12N7/04

CPC分类号： A61K39/12 ,  A61K47/26 ,  A61K47/36 ,  A61K47/42 ,  A61K2039/5254 ,  A61K2039/55555 ,  A61K2039/70 ,  C08G2650/58 ,  C08L71/02 ,  C08L2203/02 ,  C12N7/00 ,  C12N2710/10051 ,  C12N2710/10061 ,  C12N2710/24151 ,  C12N2710/24161 ,  C12N2760/16051 ,  C12N2760/16061 ,  C12N2760/18411 ,  C12N2770/24134 ,  C12N2770/24151 ,  C12N2770/24161 ,  C12N2770/36151 ,  C12N2770/36161 ,  Y02A50/386 ,  Y02A50/388 ,  Y02A50/39 ,  Y02A50/394 ,  Y02A50/396

摘要： The present invention is related to a live, attenuated virus composition comprising: one or more live, attenuated viruses; one or more albumins selected from the group consisting of lactalbumins and serum albumins, and trehalose, wherein the composition is capable of reducing the inactivation of the live, attenuated virus.

摘要翻译： 本发明涉及活的减毒病毒组合物，其包含：一种或多种活的，减毒的病毒; 选自哺乳动物和血清白蛋白的一种或多种白蛋白和海藻糖，其中所述组合物能够减少活的减毒病毒的失活。

公开(公告)号：EP2501405A1

公开(公告)日：2012-09-26

申请号：EP10832340.3

申请日：2010-11-22

申请人： Inviragen, Inc.

发明人： STINCHCOMB, Dan T. ,  OSORIO, Jorge E. ,  POWELL, Timothy D. ,  JONES, Jeremy

IPC分类号： A61K39/295 ,  A61K39/275

CPC分类号： C12N15/86 ,  A61K39/00 ,  A61K39/12 ,  A61K39/145 ,  A61K2039/5256 ,  C07K14/005 ,  C07K2319/02 ,  C12N15/863 ,  C12N2710/24134 ,  C12N2710/24143 ,  C12N2760/16034 ,  C12N2760/16122 ,  C12N2760/16134

摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions. In other embodiments, vaccine compositions are reported of use in a subject.

公开(公告)号：EP2438198A1

公开(公告)日：2012-04-11

申请号：EP10783881.5

申请日：2010-05-28

申请人： Inviragen, Inc.

发明人： STINCHCOMB, Dan T. ,  OSORIO, Jorge E. ,  PARTIDOS, Charalambos D. ,  BREWOO, Joseph N.

IPC分类号： C12Q1/70

CPC分类号： A61K39/12 ,  A61K9/0019 ,  A61K2039/5254 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/70 ,  C12N2770/24134 ,  Y02A50/386 ,  Y02A50/407

摘要： Embodiments of the present invention report compositions and methods for vaccinating a subject against dengue viruses. In some embodiments, vaccine compositions may be administered by intradermal introduction. In certain embodiments, intradermal introduction in a subject of a vaccine against dengue virus may include one or more intradermal boosts after initial vaccination. Other embodiments include intradermal injection of a vaccine composition against dengue virus wherein the composition provides protection against two or more of DEN-1, DEN-2, DEN-3 and DEN-4.