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1.发明授权
公开(公告)号：EP0646038B1
公开(公告)日：2000-11-15
申请号：EP93915384.7
申请日：1993-06-18
发明人： GIROT, Pierre , BOSCHETTI, Egisto
CPC分类号： B01D15/20 , B01D15/3804 , B01J20/103 , B01J20/28004 , B01J20/28057 , B01J20/28069 , B01J20/28078 , B01J20/288 , B01J20/3204 , B01J20/321 , B01J20/327 , B01J20/3289 , B01J39/17 , B01J39/26 , B01J41/20 , B01J2220/54 , B01J2220/58
摘要： This invention relates generally to modified porous solid supports and processes for the preparation and use of same. In particular, passivated porous mineral oxide, polymeric, or polymer-coated mineral oxide supports are disclosed which are characterized by a reversible high sorptive capacity substantially unaccompanied by non-specific adsorption of or interaction with biomolecules. Passivation is achieved by use of a passivation mixture comprising a main monomer, a passivating monomer and a crosslinking agent, which mixture upon polymerization results in the substantial elimination of the undesirable non-specific interaction with biomolecules.
摘要翻译： 本发明涉及基因的反弹到改良的多孔固体支持物和方法用于制备和使用的相同。 特别地，钝化多孔矿物氧化物，聚合物，或聚合物涂覆的无机氧化物载体是游离缺失盘其通过可逆高吸附能力通过非特异性吸附或与生物分子相互作用基本上陪伴特征的。 钝化是通过使用钝化混合物包括主单体，钝化起始单体和交联剂，其混合物当在与生物分子不期望的非特异性相互作用的基本消除聚合结果的实现。
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2.发明公开
公开(公告)号：EP1071500A1
公开(公告)日：2001-01-31
申请号：EP99916386.8
申请日：1999-04-05
发明人： VOUTE, Nicolas , BOSCHETTI, Egisto , GIROT, Pierre
CPC分类号： B01J20/26 , B01D15/1807 , B01D2215/021 , B01J20/06 , B01J20/262 , B01J20/264 , B01J20/267 , B01J20/28004 , B01J20/28097 , B01J20/286 , B01J20/3028 , B01J20/3042 , B01J20/3078 , B01J20/3204 , B01J20/327 , B01J20/3274 , B01J20/3276 , B01J20/3282 , B01J2220/42 , B01J2220/49 , B01J2220/52 , B01J2220/56 , C04B38/00 , C04B38/009 , C04B20/1029 , C04B38/0074
摘要： The present invention provides small, dense mineral oxide solid supports or microbeads, comprising dense microporous mineral oxides matrices in which a skin of polymers is rooted, and their use in downstream processing, especially for fluidized bed purification of bioparticles or high molecular weight macromolecules.
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