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公开(公告)号：EP0359831B2
公开(公告)日：2007-06-20
申请号：EP89904212.1
申请日：1989-03-30
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806
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公开(公告)号：EP0359831B1
公开(公告)日：1995-08-30
申请号：EP89904212.1
申请日：1989-03-30
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806
摘要： A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon with a space (8) defined by a spacer (7) and a cover (9). When a biological sample solution is brought into contact with the inlet (10) of the biosensor having the above-described structure, the sample solution is introduced into its inside, while the air within the space (8) is rapidly discharged through the outlet (11) and, at the same time, the space (8) is filled with the sample solution up to the neighborhood of the outlet. Thus, measurement can be conducted inexpensively at a high speed with a high accuracy through simple procedures without residual bubbles.
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公开(公告)号：EP0359831A1
公开(公告)日：1990-03-28
申请号：EP89904212.1
申请日：1989-03-30
IPC分类号： G01N27/28 , G01N27/30 , C12M1/40 , G01N27/327
CPC分类号： G01N27/3272 , C12Q1/001 , C12Q1/004 , Y10S435/817 , Y10S436/806
摘要： A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon with a space (8) defined by a spacer (7) and a cover (9). When a biological sample solution is brought into contact with the inlet (10) of the biosensor having the above-described structure, the sample solution is introduced into its inside, while the air within the space (8) is rapidly discharged through the outlet (11) and, at the same time, the space (8) is filled with the sample solution up to the neighborhood of the outlet, Thus, measurement can be conducted inexpensively at a high speed with a high accuracy through simple procedures without residual bubbles.
摘要翻译： 本发明的生物传感器包括依次形成引线（2,3,3'）的绝缘基板（1），主要由碳（4,5,5'），绝缘层（ 6）和由酶和电子受体构成的反应层（14），并且在其上设置有由间隔物（7）和盖（9）限定的空间（8）。 当生物样品溶液与具有上述结构的生物传感器的入口（10）接触时，将样品溶液引入其内部，同时空间（8）内的空气通过出口（ 11），并且同时，空间（8）填充有样品溶液直到出口附近。 因此，通过没有残留气泡的简单程序，可以高精度地以高速度廉价地进行测量。
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