-
公开(公告)号:EP3027227A1
公开(公告)日:2016-06-08
申请号:EP14832592.1
申请日:2014-07-31
申请人: Memorial Sloan Kettering Cancer Center , The Rockefeller University , Rutgers, the State University of New Jersey , University of Bonn
发明人: PATEL, Dinshaw J. , TUSCHL, Thomas , JONES, Roger , HARTMANN, Gunther , BARCHET, Winfried , ZILLINGER, Thomas , DENG, Liang , ASCANO, Manuel, Jr. , WANG, Weiyi , GAO, Pu
IPC分类号: A61K48/00
CPC分类号: G06F19/16 , A61K31/352 , A61K31/473 , A61K31/7084 , C07K14/705 , C07K14/7156 , C07K2299/00 , G01N33/68 , G01N2333/52 , G01N2400/00 , G01N2500/04 , G06F19/12
摘要: The present invention provides STING crystals. The present invention also provides STING modulators that interact with sites present in and/or defined by such crystals. The present invention also provides methods of making and using such crystals and modulators. Other aspects and/or features of the present invention will be apparent to those skilled in the art, reading the present specification.
摘要翻译: 本发明提供STING晶体。 本发明还提供了与存在于和/或由这种晶体限定的位点相互作用的STING调节剂。 本发明还提供制造和使用这种晶体和调节剂的方法。 阅读本说明书,本发明的其它方面和/或特征对于本领域技术人员是显而易见的。