公开(公告)号：EP3710058B1

公开(公告)日：2024-10-09

申请号：EP18808075.8

申请日：2018-11-15

IPC: A61K31/05 ,  A61K31/352 ,  A61K45/06 ,  A61P25/08 ,  A61K36/185

CPC classification number: A61K45/06 ,  A61K31/352 ,  A61P25/08 ,  A61K31/05 ,  A61K36/185 ,  A61K31/658

公开(公告)号：EP4426326A1

公开(公告)日：2024-09-11

申请号：EP22859531.0

申请日：2022-12-15

Applicant: Medika Natura Sdn. Bhd.

Inventor： MUSTADZA, Muhamad ,  ABDUL RAZAK, Mohd Isa

IPC: A61K36/185 ,  A61P3/00 ,  A61P3/04 ,  A61P29/00 ,  A61K31/05 ,  A61K31/192 ,  A61K31/216 ,  A61K31/7048

CPC classification number: A61K36/185 ,  A61P3/00 ,  A61P29/00 ,  A61K31/192 ,  A61K2236/1520130101 ,  A61K2236/1720130101 ,  A61K2236/3320130101 ,  A61K2236/33320130101 ,  A61P3/04 ,  A61K45/06 ,  A61K31/352 ,  A61K31/353 ,  A61K31/60 ,  A61K31/375 ,  A61K31/194 ,  A61K31/201

公开(公告)号：EP4426290A1

公开(公告)日：2024-09-11

申请号：EP22890703.6

申请日：2022-11-02

Applicant: Schedule 1 Therapeutics, Inc.

Inventor： PAPPAS, George D. ,  DUSSOR, Gregory

IPC: A61K31/352 ,  A61K31/045 ,  A61K31/05

CPC classification number: A61K31/352 ,  A61K31/05 ,  A61K31/192 ,  A61K31/658 ,  A61K45/06

公开(公告)号：EP3970707B1

公开(公告)日：2024-08-28

申请号：EP21190540.1

申请日：2017-04-11

IPC: A61K31/05 ,  A61K45/06 ,  A61K31/352 ,  A61K36/185 ,  A61P25/00 ,  A61P25/18 ,  A61P25/28

CPC classification number: A61K45/06 ,  A61K31/352 ,  A61K36/185 ,  A61K31/05 ,  A61P25/28 ,  A61P25/18

公开(公告)号：EP4417600A1

公开(公告)日：2024-08-21

申请号：EP22880202.1

申请日：2022-10-08

Applicant: Beijing Tide Pharmaceutical Co., Ltd.

Inventor： LI, Wenming ,  LI, Xiaobo ,  LU, Peng ,  PIAO, Mingnan ,  WANG, Ning ,  YU, Guokun ,  LIU, Junrong ,  ZHANG, Yu ,  YU, Tiantian

IPC: C07D311/04 ,  C07D405/14 ,  C07D209/02 ,  A61K31/403 ,  A61K31/352 ,  A61P35/00

CPC classification number: Y02P20/55 ,  A61K31/352 ,  A61K31/403 ,  A61P35/00 ,  C07D209/02 ,  C07D311/04 ,  C07D405/14

Abstract: The present invention provides compounds, or pharmaceutically acceptable salts, esters, optical isomers, stereoisomers, polymorphs, solvates, N-oxides, isotopically labeled compounds, metabolites, chelates, complexes, clathrates, or prodrugs thereof, and pharmaceutical compositions containing the compounds of the invention. Also provides the application of the compounds in preparing medicaments for treating SHP2 phosphatase modulated diseases. The invention also provides methods for treating SHP2 phosphatase modulated diseases.

公开(公告)号：EP4410286A1

公开(公告)日：2024-08-07

申请号：EP22875168.1

申请日：2022-09-30

Applicant: Shandong New Time Pharmaceutical Co., Ltd.

Inventor： ZHANG, Guimin ,  YAO, Jingchun ,  LI, Honghua ,  SUN, Chenghong ,  ZHAO, Tao

IPC: A61K31/4245 ,  A61K31/352 ,  A61P25/28 ,  A61K9/08 ,  A61K9/10 ,  A61K9/107 ,  A61K9/113 ,  A61K9/14 ,  A61K9/16 ,  A61K9/22 ,  A61K9/24 ,  A61K9/28 ,  A61K9/48

CPC classification number: A61K9/209 ,  A61K31/4245 ,  A61K9/107 ,  A61K9/20 ,  A61K9/10 ,  A61K9/14 ,  A61K9/48 ,  A61K9/16 ,  A61K9/28 ,  A61K9/08 ,  A61K9/113 ,  A61P25/28 ,  A61K31/352

Abstract: A pharmaceutical composition for preventing or treating Alzheimer's disease and use thereof are disclosed and belong to the technical field of medicines. The pharmaceutical composition includes
(Z)-3-(N-(3-bromo-4-fluorophenyl)-N'-hydroxyformamido)-4-(2-guanidinoethyl)amino)-1,2, 5-oxadiazole and anhydroicaritin. A pharmacodynamic experiment proves that the pharmaceutical composition achieves a synergistic therapeutic effect on treating Alzheimer's disease.

公开(公告)号：EP4364593A3

公开(公告)日：2024-07-31

申请号：EP24164935.9

申请日：2017-09-14

Applicant: Altria Client Services LLC

Inventor： RAICHMAN, Yossef

IPC: A24F40/42 ,  A24F40/57 ,  A24F40/20

CPC classification number: A61P25/36 ,  A61P27/06 ,  A61P25/30 ,  A61P43/00 ,  A61P11/06 ,  A61P25/18 ,  A61P25/08 ,  A61P29/00 ,  A61P1/08 ,  A61K31/05 ,  A61K31/352 ,  A24F40/50 ,  A24F40/60 ,  A24F40/20 ,  A24F40/57 ,  A24F40/46 ,  A24F40/95 ,  A61M15/06 ,  A61M11/042 ,  A61M2205/365320130101 ,  A61M19/00 ,  A61M15/003 ,  A61M2205/336820130101 ,  A61M2205/50520130101 ,  A61M2016/002120130101 ,  A61M2016/002420130101 ,  A61M2205/333420130101 ,  A61M2205/608120130101 ,  A61M2205/330620130101 ,  A61M2205/331720130101 ,  A61M2205/602720130101 ,  A61M2205/022720130101 ,  A61M2205/023820130101 ,  A61M15/0041 ,  A61M2209/08620130101 ,  A61M15/0045 ,  A61M15/0021 ,  A61M2205/820620130101 ,  A61M2205/823720130101 ,  A61M2205/826220130101 ,  A61M15/006 ,  A61M15/0063 ,  A61M2205/27320130101 ,  A61M2205/607220130101 ,  A61M2205/603620130101 ,  A61M2205/605420130101 ,  A61M2205/1020130101 ,  A61M2205/36820130101 ,  A61M2205/36220130101 ,  A61M2209/0120130101 ,  A61M2205/359220130101 ,  A61M2205/358420130101 ,  A61M15/002 ,  A61M2205/1820130101 ,  A61M2205/58320130101 ,  A61M2205/58120130101 ,  A61M2205/58220130101 ,  A61M15/0065 ,  A61M2205/0720130101 ,  A24F40/42

Abstract: Apparatus and methods are described for use with a portion of plant material (32) that includes at least one active ingredient. A vaporizing unit (21) includes a heating element (36) configured to heat the plant material, and a sensor (35) configured to detect an indication of airflow rate through the vaporizing unit. Control circuitry (34) is configured to receive an indication of the airflow rate through the vaporizing unit, and, in response thereto, to determine a smoking profile that is desired by the user. The control circuitry drives the heating element to vaporize the active ingredient of the plant material by heating the plant material according to the determined smoking profile. The control circuitry dynamically updates the smoking profile in response to changes in airflow rate over the course of a smoking session. Other applications are also described.

公开(公告)号：EP4398901A1

公开(公告)日：2024-07-17

申请号：EP22777562.4

申请日：2022-09-02

Applicant: Eisai R&D Management Co., Ltd.

Inventor： CHEN, Tenghui ,  GUALBERTO, Antonio ,  SCHOLZ, Catherine

IPC: A61K31/352 ,  A61K31/7048 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04

CPC classification number: A61K31/7048 ,  A61K31/352 ,  A61K45/06 ,  A61P35/00 ,  A61P35/04

公开(公告)号：EP4373477A2

公开(公告)日：2024-05-29

申请号：EP22726393.6

申请日：2022-04-27

Applicant: Proleukocyte AB

Inventor： WICKSTRÖM, Stina Linnéa ,  KIESSLING, Rolf ,  ARNÉR, Elias Set Jenö

IPC: A61K31/00 ,  A61K31/05 ,  A61K31/12 ,  A61K31/155 ,  A61K31/225 ,  A61K31/26 ,  A61K31/352 ,  A61K31/7135 ,  A61K39/00 ,  A61K45/06 ,  A61P35/00 ,  C07K16/00 ,  C12N5/07 ,  G01N33/50

CPC classification number: A61K31/7135 ,  A61K31/26 ,  A61K31/12 ,  A61K31/05 ,  A61P35/00 ,  A61K31/352 ,  A61K45/06 ,  A61K31/155 ,  A61K31/225 ,  A61K31/00 ,  C12N5/0636 ,  C12N5/0646 ,  C12N2501/6020130101 ,  C12N2501/230220130101 ,  C07K16/2887 ,  A61K39/395 ,  C12N2501/99920130101 ,  A61K39/4611 ,  A61K39/464424 ,  A61K39/464452 ,  A61K39/464412 ,  A61K39/4613 ,  A61K39/4631

公开(公告)号：EP4373303A1

公开(公告)日：2024-05-29

申请号：EP22750878.5

申请日：2022-07-21

Applicant: Nicoventures Trading Limited

Inventor： ALDERMAN, Steven L ,  POOLE, Thomas ,  TALUSKIE, Karen ,  WILBERDING, Kathryn L ,  HAWKE, Jenni ,  DAVIES, Ashley ,  DANIEL, Michael S ,  TANG, Kai ,  XU, Keyi ,  MCQUILLAN, Karina ,  CARAWAY, John

IPC: A24B15/16 ,  A24B13/00 ,  A23L2/395 ,  A23L2/52 ,  A61K31/352 ,  A61K9/00 ,  A61K9/70

CPC classification number: A24B15/16 ,  A24B13/00 ,  A61K31/352 ,  A61K9/0095 ,  A61K9/0053 ,  A61K9/0058 ,  A61K9/0056 ,  A61K47/38 ,  A61K47/32 ,  A61K47/26 ,  A61K47/20 ,  A61K47/44 ,  A61K47/10 ,  A61K47/24 ,  A61K31/05 ,  A23L33/105 ,  A23L27/10 ,  A61K36/185 ,  A23L2/395 ,  A23L2/52 ,  A24B15/303 ,  A61K9/006