-
1.发明授权PROCESS FOR THE PREPARATION OF 3,4-DIHYDROXYBUTANOIC ACID AND DERIVATIVES THEREOF FROM SUBSTITUTED PENTOSE SUGARS 有权用于生产3,4-DIHYDROBUTANSÄURE及其衍生物的由取代的戊糖
公开(公告)号：EP1173400B1
公开(公告)日：2006-08-02
申请号：EP00908716.4
申请日：2000-02-17
CPC分类号： C07D307/33 , C07C51/285 , C07C59/10
摘要： A process for the preparation of 3,4-dihydroxybutanoic acid (I) and 3-hydroxy-η-butyrolactone (V) thereof from a 3-leaving group substituted pentose source is described. In particular, the process relates to the synthesis of (R)-3,4-dihydroxybutanoic acid and (R)-3-hydroxy-η-butyrolactone from a 3-leaving group substituted L-pentose sugars. The process uses a base and a peroxide to convert the pentose source to the chiral 3,4-dihydroxybutanoic acid compound. The chiral 3,4-dihydroxybutanoic acid can be further converted to 3-hydroxy-η-butyrolactone by acidification. The chiral compound is useful as a chemical intermediate to the synthesis of various drugs and other products.
-
2.发明公开PROCESS FOR THE PREPARATION OF 3,4-DIHYDROXYBUTANOIC ACID AND DERIVATIVES THEREOF FROM SUBSTITUTED PENTOSE SUGARS 有权用于生产3,4-DIHYDROBUTANSÄURE及其衍生物的由取代的戊糖
公开(公告)号：EP1173400A1
公开(公告)日：2002-01-23
申请号：EP00908716.4
申请日：2000-02-17
CPC分类号： C07D307/33 , C07C51/285 , C07C59/10
摘要： A process for the preparation of 3,4-dihydroxybutanoic acid (I) and 3-hydroxy-η-butyrolactone (V) thereof from a 3-leaving group substituted pentose source is described. In particular, the process relates to the synthesis of (R)-3,4-dihydroxybutanoic acid and (R)-3-hydroxy-η-butyrolactone from a 3-leaving group substituted L-pentose sugars. The process uses a base and a peroxide to convert the pentose source to the chiral 3,4-dihydroxybutanoic acid compound. The chiral 3,4-dihydroxybutanoic acid can be further converted to 3-hydroxy-η-butyrolactone by acidification. The chiral compound is useful as a chemical intermediate to the synthesis of various drugs and other products.
-
3.发明授权
公开(公告)号：EP1324989B1
公开(公告)日：2006-06-14
申请号：EP01953494.0
申请日：2001-07-16
IPC分类号： C07D263/14 , C07D263/24
CPC分类号： C07D263/24 , C07B2200/05
摘要： A method for preparing protected, preferably chiral, 5-trityloxymethyl-oxazolidinone in one step directly from optically active 3-hydroxy-4-trityloxybutyramide is described. Oxazolidinones are animportant class of molecules in the pharmaceutical industry especially in the areas of antimicrobials and behavioral disorders.
-
4.发明公开
公开(公告)号：EP1324989A1
公开(公告)日：2003-07-09
申请号：EP01953494.0
申请日：2001-07-16
IPC分类号： C07D263/14
CPC分类号： C07D263/24 , C07B2200/05
摘要： A method for preparing protected, preferably chiral, 5-trityloxymethyl-oxazolidinone in one step directly from optically active 3-hydroxy-4-trityloxybutyramide is described. Oxazolidinones are animportant class of molecules in the pharmaceutical industry especially in the areas of antimicrobials and behavioral disorders.
-
5.发明公开PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYL 2-OXAZOLIDINONE AND NOVEL INTERMEDIATE 有权用于生产5-羟甲基-2-恶唑烷酮和新的中间
公开(公告)号：EP1324988A1
公开(公告)日：2003-07-09
申请号：EP01959057.9
申请日：2001-07-19
IPC分类号： C07D263/06
CPC分类号： C07D263/24
摘要： A process for preparing 5-hydroxymethyl-2-oxazolidinone (1), preferably optically active, in one step from 3,4-boronic acid ester protected 3,4-dihydroxybutyramides (2) is described. The oxazolidinone is important in the pharmaceutical industry especially in the areas of antimicrobials and behavioral disorders.
-
6.发明公开PREPARATION OF CROSS-LINKED 2-DIMENSIONAL POLYMERS WITH SIDEDNESS FROM $g(a),$g(b)-LACTONES 有权交联的二维聚合物与不对称$ G（a）中，$ G（b）中的内酯的制备
公开(公告)号：EP1124882A1
公开(公告)日：2001-08-22
申请号：EP99948335.7
申请日：1999-09-20
CPC分类号： H01L23/5328 , A61L27/18 , A61L33/068 , C08G69/04 , C08G69/08 , C08G69/28 , C09D177/00 , H01L21/288 , H01L23/49883 , H01L51/0021 , H01L2924/0002 , H01L2924/12044 , C08L77/00 , H01L2924/00
摘要： Polymers and processes for synthesizing the polymers from α,β-unsaturated lactones, particularly 2(5H)-furanone, and amines with side chains. The polymers are used as hydrogels, as polymers that can bind metals and form complexes that are soluble in organic solvents, as polymers useful as flocculants in water purification, as polymers useful on non-fouling surfaces for biofilm suppression, polymers for use on non-thrombogenic surfaces, and polymers with uses as thin conductive films for microchips and other electronic devices. The process is a polymerization reaction involving the cyclic-α,β-unsaturated lactone and a primary amine or primary ammonium compound.
-
7.发明授权PREPARATION OF CROSS-LINKED 2-DIMENSIONAL POLYMERS WITH SIDEDNESS FROM $g(a),$g(b)-LACTONES 有权交联的二维聚合物与不对称$ G（a）中，$ G（b）中的内酯的制备
公开(公告)号：EP1124882B1
公开(公告)日：2005-08-17
申请号：EP99948335.7
申请日：1999-09-20
CPC分类号： H01L23/5328 , A61L27/18 , A61L33/068 , C08G69/04 , C08G69/08 , C08G69/28 , C09D177/00 , H01L21/288 , H01L23/49883 , H01L51/0021 , H01L2924/0002 , H01L2924/12044 , C08L77/00 , H01L2924/00
-
8.发明授权PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYL 2-OXAZOLIDINONE AND NOVEL INTERMEDIATE 有权用于生产5-羟甲基-2-恶唑烷酮和新的中间
公开(公告)号：EP1324988B1
公开(公告)日：2005-02-09
申请号：EP01959057.9
申请日：2001-07-19
IPC分类号： C07D263/06 , C07D263/24
CPC分类号： C07D263/24
摘要： A process for preparing 5-hydroxymethyl-2-oxazolidinone (1), preferably optically active, in one step from 3,4-boronic acid ester protected 3,4-dihydroxybutyramides (2) is described. The oxazolidinone is important in the pharmaceutical industry especially in the areas of antimicrobials and behavioral disorders.
-
公开(公告)号：EP1027343B1
公开(公告)日：2002-12-04
申请号：EP98948584.2
申请日：1998-09-29
IPC分类号： C07D307/32 , C07C69/675 , C07C27/06 , C07C27/08
CPC分类号： C07D315/00
摘要： Preparation of 4-hydroxy substituted butyrolactones is described. A process for the preparation of 3-hydroxybutyrolactone, 1,2,4-trihydroxybutane and 3,4-dihydroxy acid methyl ester from malic acid is particularly described. The preparation of 4-hydroxymethyl-4-hydroxybutyric acid-1-methyl ester and 4-hydroxymethyl butyrolactone is particularly described. The compounds are intermediates to various pharmaceutical and agricultural products.
-
10.发明公开PROCESS FOR THE PREPARATION OF 1,5-DIDEOXY-1,5-IMINO HEXITOLS FROM OXIMES OR IMINES 审中-公开用于生产1,5-二脱氧-1,5-亚胺基己糖OFF肟或亚胺
公开(公告)号：EP1181277A1
公开(公告)日：2002-02-27
申请号：EP01920835.4
申请日：2001-03-28
IPC分类号： C07D211/36 , C07H5/04 , C07H5/06 , C07H15/00
CPC分类号： C07D211/76 , C07D211/46
摘要： A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
-
-
-
-
-
-
-
-
-
搜索结果
24 条记录 (耗时 0.012 秒)
