专利检索 ap:("N.V. Organon" OR "Pharmacopeia, LLC") AND inv:"WIJKMANS, Jacobus Cornelis Henricus Maria" 第 1 页

1.

发明公开
PYRROLO[2,3-d]PYRIMIDIN-2-YL-AMINE DERIVATIVES AS PKC-THETA INHIBITORS 审中-公开
标题翻译：吡咯并[2,3-D-]嘧啶-2-YL-氨基衍生物PKC-THETA-HEMMER

公开(公告)号：EP2294071A1

公开(公告)日：2011-03-16

申请号：EP09729779.0

申请日：2009-04-08

申请人： N.V. Organon , Pharmacopeia, LLC

发明人： ROUGHTON, Andrew Laird , HO, Koc-Kan , OHLMEYER, Michael , DILLER, David , NEAGU, Irina , KINGSBURY, Celia , CHAN, Jui-Hsiang , LOMMERSE, Johannes, Petrus, Maria , TEERHUIS, Neeltje, Miranda , WIJKMANS, Jacobus Cornelis Henricus Maria , PLATE, Ralf

IPC分类号： C07D487/04 , A61K31/519

CPC分类号： C07D487/04

摘要： The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said pyrrolo[2,3-d]pyrimidine-2-ylamine derivatives and to their use in therapy, for instance in the treatment of PKCθ mediated disorders.

2.

发明公开
PURINES AS PKC-THETA INHIBITORS 审中-公开
标题翻译：嘌呤AS PKC抑制剂THETA

公开(公告)号：EP2078019A2

公开(公告)日：2009-07-15

申请号：EP07844441.1

申请日：2007-10-19

申请人： N.V. Organon , Pharmacopeia, Inc.

发明人： NEAGU, Irina , ROUGHTON, Andrew , HO, Koc-Kan , DILLER, David , CHAN, Jui Hsiang , KINGSBURY, Celia , OHLMEYER, Michael , WIJKMANS, Jacobus Cornelis Henricus Maria , TEERHUIS, Neeltje Miranda , LOMMERSE, Johannes Petrus Maria

IPC分类号： C07D473/32 , A61K31/52 , A61P35/00

CPC分类号： C07D473/32

摘要： A chemical genus of purines, which are useful as PKCϑ inhibitors, is disclosed. The genus is represented by the formula (I); A representative example is: (II)