公开(公告)号：EP3286361A1

公开(公告)日：2018-02-28

申请号：EP16784102

申请日：2016-04-25

申请人： NANTOMICS LLC ,  NANT HOLDINGS IP LLC

发明人： NGUYEN ANDREW ,  NIAZI KAYVAN ,  SOON-SHIONG PATRICK ,  RABIZADEH SHAHROOZ ,  BENZ STEPHEN CHARLES

IPC分类号： C40B30/02 ,  A61K35/17 ,  A61K49/00 ,  A61P35/00 ,  C07K16/00

CPC分类号： A61K35/17 ,  C07K16/005 ,  C07K16/30 ,  C07K16/32 ,  C07K2317/32 ,  G06F19/18 ,  G06F19/22

摘要： Contemplated compositions and methods are directed to cancer neoepitopes and uses of such neoepitopes, especially to generate synthetic antibodies against neoepitopes that may then be employed in the manufacture of a therapeutic agent. Preferred therapeutic agents will comprise a synthetic antibody against a neoepitope, and most preferably in combination with a cellular or non-cellular component for use as a diagnostic or therapeutic agent.

公开(公告)号：EP3221472A4

公开(公告)日：2017-11-22

申请号：EP15860469

申请日：2015-11-20

申请人： NANTOMICS LLC

发明人： RABIZADEH SHAHROOZ ,  NIAZI KAYVAN ,  BENZ STEPHEN CHARLES ,  NGUYEN ANDREW

IPC分类号： C12Q1/70 ,  C12Q1/68 ,  G06F19/20

CPC分类号： C12Q1/70 ,  G06F19/20 ,  G06F19/22

摘要： Systems and methods are provided for determination of primers for differentiation of at least two unspecified pathogens that belong to distinct pathogen (e.g., virus) families that comprise multiple distinct pathogen species and/or varieties.