公开(公告)号：EP2004693A2

公开(公告)日：2008-12-24

申请号：EP07754114.2

申请日：2007-03-29

申请人： NOVARTIS AG ,  Novartis Pharma GmbH

发明人： STOVER, David Raymond ,  PRASSLER, Josef ,  BERGER, Catrin ,  BROCKS, Bodo

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61P35/00 ,  A61P29/00 ,  G01N33/00 ,  C12N15/13 ,  C12N15/85 ,  A61K47/48 ,  A61K38/00 ,  A61K31/00

CPC分类号： C07K16/2863 ,  C07K2317/21 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  Y10S435/81

摘要： Antibodies and fragments that bind to the protein target c Met, particularly to epitopes located in the c Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a c Met-related condition such as a cancer, a metastasis, or an inflammatory condition.

公开(公告)号：EP2004693B1

公开(公告)日：2012-06-06

申请号：EP07754114.2

申请日：2007-03-29

申请人： Novartis AG ,  Novartis Pharma GmbH

发明人： STOVER, David Raymond ,  PRASSLER, Josef ,  BERGER, Catrin ,  BROCKS, Bodo

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61P35/00 ,  A61P29/00 ,  G01N33/00 ,  C12N15/13 ,  C12N15/85 ,  A61K47/48 ,  A61K38/00 ,  A61K31/00

CPC分类号： C07K16/2863 ,  C07K2317/21 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  Y10S435/81

摘要： Antibodies and fragments that bind to the protein target c Met, particularly to epitopes located in the c Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a c Met-related condition such as a cancer, a metastasis, or an inflammatory condition.