公开(公告)号：EP0969909A1

公开(公告)日：2000-01-12

申请号：EP98961504.2

申请日：1998-12-24

申请人： Organo Corporation

发明人： KANEKO, Kikuzo,Organo Corporation ,  MASUDA, Takayuki,Organo Corporation ,  MATSUDA, Fumihiko,Organo Corporation ,  SATO, Kohei,Organo Corporation ,  TANIKAWA, Kouji,Organo Corporation

IPC分类号： B01D15/08 ,  B01D53/02 ,  G01N30/46 ,  C07H1/06 ,  C13J1/08 ,  C13K3/00

CPC分类号： G01N30/466 ,  B01D15/1828 ,  B01D15/1842 ,  B01D15/361 ,  B01D53/02 ,  B01D53/025 ,  B01D2215/023 ,  C07H3/02 ,  C07H3/04 ,  C07H3/06 ,  C13B20/14 ,  C13B20/144 ,  C13B20/148 ,  C13B35/06 ,  C13K3/00 ,  C13K13/005 ,  G01N30/02 ,  B01D15/36

摘要： In chromatographic separation in a plurality of steps with a chromatographic separator packed with an ion exchanger used as at least part of chromatographic packing, at least part of the ionic form of at least part of the ion exchanger is changed to an ionic form fit for separation of components to be separated in each step to effect chromatographic separation, whereby a starting fluid material containing at least 3 components can be efficiently separated into at least 3 fractions. A preferred example of the chromatographic separator comprises a group of packing bed units (1, 2, ...10) linked in endless series to form a circulation flow path (10, 11, 1, 2, ...10), and is provided with a shutoff valve (2) at a position of the circulation flow path, starting fluid material feed means (30), desorbent feed means (31) and 2-fraction withdrawal means (12, 14) for all the packing bed units (1, 2, ...10), and a single-fraction withdrawal means (13) connected to the circulation flow path on the upstream side of the shutoff valve and without any packing bed unit therebetween.