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公开(公告)号：EP2160235B1
公开(公告)日：2016-11-30
申请号：EP08827282.8
申请日：2008-05-30
发明人： OUYANG, Zheng , GAO, Liang , COOKS, Robert, Graham
CPC分类号： H01J49/24 , H01J49/00 , H01J49/0013 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/04 , H01J49/0404 , H01J49/0422 , H01J49/0495 , H01J49/10 , H01J49/165 , H01J49/26
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公开(公告)号：EP4099363A1
公开(公告)日：2022-12-07
申请号：EP22180839.7
申请日：2014-04-21
摘要： The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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5.发明公开SAMPLE ANALYSIS SYSTEMS AND METHODS OF USE THEREOF 审中-公开VERFAHREN ZUR VERWENDUNG的PROBENANALYSYSYSTEM
公开(公告)号：EP3155640A2
公开(公告)日：2017-04-19
申请号：EP15809806.1
申请日：2015-06-16
发明人： COOKS, Robert, Graham , BAIRD, Zane , WEI, Pu
IPC分类号： H01J49/26
CPC分类号： H01J49/24 , G01N27/622 , H01J49/0013 , H01J49/061 , H01J49/142
摘要： The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.
摘要翻译： 本发明一般涉及样品分析系统及其使用方法。 在某些方面，本发明提供了一种用于分析样品的系统，该样品包括被配置为从样品产生离子的离子发生器。 该系统还包括离子分离器，该离子分离器构造成在大气压力或高于大气压下从离子发生器接收的离子分离而不使用层流气体，以及接收和检测分离的离子的检测器。
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公开(公告)号：EP4153352A1
公开(公告)日：2023-03-29
申请号：EP21808528.0
申请日：2021-03-18
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公开(公告)号：EP3607575A1
公开(公告)日：2020-02-12
申请号：EP18771480.3
申请日：2018-03-22
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公开(公告)号：EP3014647A1
公开(公告)日：2016-05-04
申请号：EP14818223.1
申请日：2014-04-21
CPC分类号： H01J49/0445 , C12N13/00 , C12Q1/04 , G01N2560/00 , H01J49/16
摘要： The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
摘要翻译： 本发明总体上涉及用于样品中微生物的质谱分析的系统和方法。 多孔材料（例如滤纸或类似材料）用于保持和传输液体，并且当对材料施加高电压时，离子直接从材料的边缘产生。 多孔材料与溶剂流保持离散（即分开或断开）。 相反，将样品点在多孔材料上或将多孔材料弄湿并用于擦拭含有样品的表面。 然后将具有点样或拭子样品的多孔材料弄湿并连接到高压源以产生随后分析的样品的离子。 样品通过多孔材料运输，不需要单独的溶剂流。
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公开(公告)号：EP2338160A1
公开(公告)日：2011-06-29
申请号：EP09821010.7
申请日：2009-10-05
发明人： OUYANG, Zheng , COOKS, Robert, Graham , GARIMELLA, Sandilya, Venkata , HARPER, Jason, D. , CHARIPAR, Nicholas, A.
IPC分类号： H01J49/00
CPC分类号： H01J49/0404 , G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/04 , H01J49/0409 , H01J49/0422 , H01J49/0459 , H01J49/10 , H01J49/26 , H01J49/40 , H01J49/4215
摘要： The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
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公开(公告)号：EP2160235A2
公开(公告)日：2010-03-10
申请号：EP08827282.8
申请日：2008-05-30
发明人： OUYANG, Zheng , GAO, Liang , COOKS, Robert, Graham
CPC分类号： H01J49/24 , H01J49/00 , H01J49/0013 , H01J49/0027 , H01J49/0031 , H01J49/004 , H01J49/04 , H01J49/0404 , H01J49/0422 , H01J49/0495 , H01J49/10 , H01J49/165 , H01J49/26
摘要： A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.
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