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1.发明授权Dimethyl sulfoxide adducts of sodium 6-(D(-)-alpha-(4-hydroxy-1,5-naphthyridine-3-carboxamido)phenylacetamido)penicillanate or the derivative thereof bearing a hydroxyl group at the p-position of the phenyl group, methods for their preparation and decomposition, and their use as intermediates for purifying the crude penicillins 失效6-（D（ - ） - 丙氨酸 - （4-羟基-1,5-萘啶-3-羧基甲酰胺）苯基乙胺酸钠的二甲基硅氧烷添加剂或其衍生物在苯基的P位上承载羟基 ，其制备和分解方法，以及作为中和剂用于制备原料的方法
公开(公告)号：EP0006688B1
公开(公告)日：1982-05-19
申请号：EP79300992.9
申请日：1979-05-30
IPC分类号： C07D499/22 , C07D499/18
CPC分类号： C07D471/04 , C07D499/00
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2.发明公开Dimethyl sulfoxide adducts of sodium 6-(D(-)-alpha-(4-hydroxy-1,5-naphthyridine-3-carboxamido)phenylacetamido)penicillanate or the derivative thereof bearing a hydroxyl group at the p-position of the phenyl group, methods for their preparation and decomposition, and their use as intermediates for purifying the crude penicillins 失效钠6的二甲亚砜的加合物（ - ） - D（α-（4-羟基-1,5-萘啶-3-甲酰氨基）苯基乙酰氨基）青霉烷酸及其对苯基4-羟基衍生物，它们的制备方法和切割以及它们的 使用如在粗Peniciline的纯化中间体。
公开(公告)号：EP0006688A1
公开(公告)日：1980-01-09
申请号：EP79300992.9
申请日：1979-05-30
IPC分类号： C07D499/22 , C07D499/18
CPC分类号： C07D471/04 , C07D499/00
摘要： Sodium 6- D (―)[-α-(4-hydroxy-1,5-naphtthydridine-3-carboxyamido) phenylacetamido] penicillanate or the derivative thereof bearing alydroxylgroup at the p-position of the phenyl group in a crude state can be purified efficiently through the reaction with dimethyl-sulfoxide in a liquid medium and decomposition of the obtained adducts in a water-containing liquid medium.
摘要翻译： 钠6-D（ - ）[ - α - （4-羟基-1,5- naphtthydridine -3-羧基酰氨基）苯基乙酰氨基〕青霉烷酸钠或其衍生物在苯基的对位中的粗状态轴承alydroxylgroup可以是 通过在含有水的液体介质与二甲亚砜的反应在所得到的加合物的液体介质和分解有效地净化。
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