公开(公告)号：EP2160607A1

公开(公告)日：2010-03-10

申请号：EP08756407.6

申请日：2008-05-29

申请人： Sanofi-Aventis

发明人： PEPPARD, Jane V. ,  MEHDI, Shujaath ,  LI, Zhuyin ,  DUGUID, Mei S.

IPC分类号： G01N33/58

CPC分类号： G01N33/542 ,  C12Q1/37 ,  C12Q1/44 ,  G01N2333/916 ,  G01N2333/96433 ,  G01N2500/04

摘要： The present invention provides methods for the detection of agents that modify the activity of the N-acylphosphatidylethanolamine-hydrolysing phospholipase D (NAPE-PLD) enzyme or the Alpha/beta-hydrolase-4 (Abh4) enzyme. The disclosed methods are configured in an assay format amenable to high throughput screening applications.