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公开(公告)号：EP1948213B1
公开(公告)日：2009-02-04
申请号：EP06838008.8
申请日：2006-11-17
CPC分类号： G01N33/6893 , A61K38/00 , A61K38/45 , A61K51/00 , C07K16/18 , C07K2317/55 , C07K2317/76 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2320/32 , C12Y205/01018 , G01N33/574 , G01N33/94 , G01N2800/44 , G01N2800/7028
摘要： Embodiments of the invention are directed to methods for predicting the resistance of cancer to members of the taxoid family by measuring the levels of prohibitin. Methods for treating cancer and taxoid family member resistant cancers using inhibitors of prohibitin, as well as therapeutic complexes that target prohibitin are also provided.
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公开(公告)号：EP1948213A2
公开(公告)日：2008-07-30
申请号：EP06838008.8
申请日：2006-11-17
IPC分类号： A61K38/08
CPC分类号： G01N33/6893 , A61K38/00 , A61K38/45 , A61K51/00 , C07K16/18 , C07K2317/55 , C07K2317/76 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2320/32 , C12Y205/01018 , G01N33/574 , G01N33/94 , G01N2800/44 , G01N2800/7028
摘要： Embodiments of the invention are directed to methods for predicting the resistance of cancer to members of the taxoid family by measuring the levels of prohibitin. Methods for treating cancer and taxoid family member resistant cancers using inhibitors of prohibitin, as well as therapeutic complexes that target prohibitin are also provided.
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公开(公告)号：EP3889139A1
公开(公告)日：2021-10-06
申请号：EP21156104.8
申请日：2016-11-30
发明人： ZETTER, Bruce, R. , SUN, Lijun
IPC分类号： C07D235/32 , C07D405/12 , A61P35/00 , A61K31/4184
摘要： The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating and/or preventing proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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