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公开(公告)号：EP2399934A4
公开(公告)日：2013-03-20
申请号：EP10743590
申请日：2010-02-20
申请人： UNIV TOKYO , PERSEUS PROTEOMICS INC
发明人： HAMAKUBO TAKAO , MOCHIZUKI YASUHIRO , ABURATANI HIROYUKI , IWANARI HIROKO , NIWA SHUNSUKE , NAKADA YOSHIKO
CPC分类号： A61K51/1072 , A61K39/00 , A61K51/1054 , A61K51/1057 , A61K51/106 , A61K51/1063 , A61K51/1066 , C07K16/28 , C07K16/30 , C07K2317/34 , C07K2317/732 , G01N33/53 , G01N33/574
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公开(公告)号：EP2399993A4
公开(公告)日：2013-07-03
申请号：EP10743584
申请日：2010-02-19
申请人： UNIV TOKYO , PERSEUS PROTEOMICS INC
CPC分类号： B82Y5/00 , A61K47/6898 , C07K14/36 , C07K16/14 , C07K2317/56 , C07K2317/622 , C07K2317/92
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公开(公告)号：EP2011513A4
公开(公告)日：2010-05-26
申请号：EP07737095
申请日：2007-04-23
申请人： UNIV TOKYO , PERSEUS PROTEOMICS INC
发明人： IWATSUBO TAKESHI , KODAMA TATSUHIKO , HAMAKUBO TAKAO , TOMITA TAISUKE , HAYASHI IKUO , URANO YASUOMI , IWANARI HIROKO , OHKUCHI MASAO
IPC分类号： A61K39/395 , A61P25/28 , A61P35/00 , A61P43/00 , C12N15/09 , G01N33/15 , G01N33/50 , G01N33/53
CPC分类号： G01N33/6896 , A61K2039/505 , C07K16/40 , C07K2317/73 , C07K2317/76 , G01N33/574 , G01N2333/948 , G01N2500/02
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4.发明公开DRUG FOR DIAGNOSING COLON CANCER AND/OR COLON POLYP, OBSERVING POSTOPERATIVE COURSE AND MONITORING REOCCURRENCE 审中-公开药物诊断癌症和迪克OR /结肠息肉，观察术后课程和经常性监控装置的
公开(公告)号：EP1826567A4
公开(公告)日：2009-12-09
申请号：EP05816756
申请日：2005-12-14
申请人： PERSEUS PROTEOMICS INC , UNIV TOKYO
发明人： ABURATANI HIROYUKI , SHIMAMURA TAKAHIRO , WATANABE KIYOTAKA , ASANO TAKEHARU , OHNISHI SHIN , HAMAKUBO TAKAO , SUGIYAMA AKIRA , HOSOMI NAOKI , IWANARI HIROKO , ISHII KEISUKE
IPC分类号： G01N33/574
CPC分类号： G01N33/57419
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公开(公告)号：EP1947460A4
公开(公告)日：2009-02-18
申请号：EP06832519
申请日：2006-11-10
申请人： UNIV TOKYO , PERSEUS PROTEOMICS INC
发明人： KODAMA TATSUHIKO , HAMAKUBO TAKAO , MAEMURA KOJI , SUGIYAMA AKIRA , IWANARI HIROKO , KOHNO ISAO , ITO YUKIO
IPC分类号： G01N33/68 , C07K16/18 , C12N15/09 , G01N33/53 , G01N33/577
CPC分类号： C07K16/18 , G01N33/577 , G01N33/6893 , G01N2800/324 , Y10S435/81
摘要： A method of judging vascular disorders as a risk factor of myocardial infarction, angiopathic dementia, etc. at an early date, namely, mild vascular disorders. There is provided a method of judging the degree of mild vascular disorders, characterized in that the level of PTX3 in a test sample is measured with the use of anti-PTX3 monoclonal antibody.
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公开(公告)号：EP1720014A4
公开(公告)日：2008-01-16
申请号：EP05719479
申请日：2005-02-24
发明人： KODAMA TATSUHIKO , HAMAKUBO TAKAO , ITO YUKIO , IWANARI HIROKO , OHKUCHI MASAO , SUGIYAMA AKIRA
CPC分类号： G01N33/6893 , G01N2500/00 , G01N2800/328
摘要： It is intended to provide a method of judging the extent of vasculopathy and a method of screening a remedy for vasculopathy. Namely, a method of judging the extent of vasculopathy characterized by comprising measuring the concentration of PTX3 in a test sample.
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7.发明公开
公开(公告)号：EP2865384A4
公开(公告)日：2016-01-20
申请号：EP13807573
申请日：2013-06-21
申请人： UNIV TOKYO
发明人： HAMAKUBO TAKAO , TSUMOTO KOUHEI , DAIGO KENJI , INOUE KENJI , YAMAGUCHI NAOTAKA , MIZUUCHI MOTOAKI , FUJII HIROYA
CPC分类号： C07K14/47 , A61K38/00 , G01N33/6875
摘要： The present invention provides a therapeutic or prophylactic agent for systemic inflammatory response syndrome (SIRS), which contains a polypeptide comprising an amino acid sequence the same or substantially the same as the amino acid sequence of the N-terminal domain of pentraxin 3 capable of binding to histone to form a polypeptide aggregate, or a pharmacologically acceptable salt thereof. The present invention also provides a reagent for quantification and a quantification method of histone, which utilize the polypeptide or a pharmacologically acceptable salt thereof. Furthermore, the present invention provides a polypeptide aggregate containing the polypeptide or a pharmacologically acceptable salt thereof and histone and a production method thereof.
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8.发明公开MONOCLONAL ANTIBODY CAPABLE OF SPECIFICALLY RECOGNIZING ASPARAGINE SYNTHASE 有权单克隆抗体特异性ASPARAGINSYNTHASE检测
公开(公告)号：EP2772501A4
公开(公告)日：2015-04-08
申请号：EP12838050
申请日：2012-10-03
发明人： HAMAKUBO TAKAO , MOCHIZUKI YASUHIRO , IWANARI HIROKO , ARAI OSAMU , KITOH TOSHIYUKI , TSURUSAWA MASAHITO
IPC分类号： C07K16/40 , C12N5/10 , C12P21/08 , G01N33/573 , G01N33/574
CPC分类号： G01N33/57496 , C07K16/40 , G01N33/573 , G01N33/574
摘要： It is an object of the present invention to provide a monoclonal antibody, which is suitable for the quantitative analysis of asparagine synthetase in a cell. The present invention provides a monoclonal antibody which specifically recognizes asparagine synthetase that is present in a cell.
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