公开(公告)号：EP3978073A1

公开(公告)日：2022-04-06

申请号：EP20815167.0

申请日：2020-05-29

申请人： Ube Industries, Ltd.

发明人： KOMORI, Ken-ichi ,  NISHIYAMA, Hayato ,  KINOSHITA, Naoya ,  WADA, Yukinori ,  MORISHITA, Kousuke ,  NINOMIYA, Akishi ,  SHIRAISHI, Yuusuke ,  ONUMA, Kazuhiro ,  OGI, Sayaka ,  KAWADA, Hiroyoshi ,  KIMURA, Tomio

IPC分类号： A61P13/12 ,  A61P43/00 ,  C07D413/10 ,  C07D498/04 ,  A61K31/553

摘要： The present invention provides a compound having Keap1 inhibitory effects and a pharmaceutical composition containing the same. Specifically, the present invention provides a compound represented by the following general formula (I):

[wherein the symbols have the same meanings as those described in the description] or a pharmaceutically acceptable salt thereof and a pharmaceutical composition containing the same.

公开(公告)号：EP3333163A1

公开(公告)日：2018-06-13

申请号：EP16833140.3

申请日：2016-08-05

申请人： UBE Industries, Ltd.

发明人： KOMORI, Ken-ichi ,  NINOMIYA, Akishi ,  USHIYAMA, Shigeru ,  SHINOHARA, Masaru ,  ITO, Koji ,  KAWAGUCHI, Tetsuo ,  TOKUNAGA, Yasunori ,  KAWADA, Hiroyoshi ,  YAMADA, Haruka ,  SHIRAISHI, Yusuke ,  KOJIMA, Masahiro ,  ITO, Masaaki ,  KIMURA, Tomio

IPC分类号： C07D401/04 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/695 ,  A61P3/10 ,  A61P13/12 ,  A61P43/00 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D413/14 ,  C07F7/18

CPC分类号： A61K31/4427 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/695 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D413/14 ,  C07F7/18 ,  Y02P20/55

摘要： The present invention provides a compound of general formula (I) (wherein, R 1 , X, p and q are as described in the present description and claims), or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing that compound.