公开(公告)号：EP2838899B1

公开(公告)日：2016-10-05

申请号：EP13701119.3

申请日：2013-01-25

申请人： Université de Lorraine ,  Centre National de la Recherche Scientifique (CNRS)

发明人： BOISBRUN, Michel ,  CHAPLEUR, Yves ,  BORDESSA, Andrea ,  FLAMENT, Stéphane ,  GRILLIER-VUISSOZ, Isabelle ,  KUNTZ, Sandra

IPC分类号： C07D417/12 ,  C07D277/34 ,  C07D417/06 ,  C07D417/14 ,  C07D311/66 ,  A61K31/427 ,  A61P35/00

CPC分类号： C07D417/14 ,  C07D277/34 ,  C07D311/66 ,  C07D311/74 ,  C07D417/06 ,  C07D417/12

公开(公告)号：EP2838899A1

公开(公告)日：2015-02-25

申请号：EP13701119.3

申请日：2013-01-25

申请人： Université de Lorraine ,  Centre National de la Recherche Scientifique (CNRS)

发明人： BOISBRUN, Michel ,  CHAPLEUR, Yves ,  BORDESSA, Andrea ,  FLAMENT, Stéphane ,  GRILLIER-VUISSOZ, Isabelle ,  KUNTZ, Sandra

IPC分类号： C07D417/12 ,  C07D277/34 ,  C07D417/06 ,  C07D417/14 ,  C07D311/66 ,  A61K31/427 ,  A61P35/00

CPC分类号： C07D417/14 ,  C07D277/34 ,  C07D311/66 ,  C07D311/74 ,  C07D417/06 ,  C07D417/12

摘要： The present invention relates to thiazolidinedione derivatives, to the processes for preparing same and to the therapeutic use thereof for preventing or treating cancer, and more specifically breast cancer. These compounds are of formula (I) and exhibit, at a concentration of 100 µM, a hepatocyte viability preferably greater than 60%, preferably greater than 80% and more preferentially greater than 85%.

公开(公告)号：EP3939497A1

公开(公告)日：2022-01-19

申请号：EP20382637.5

申请日：2020-07-15

申请人： Fundación Imdea Nanociencia ,  Centre National de la Recherche Scientifique (CNRS) ,  Scuola Internazionale Superiore Di Studi Avanzati ,  Consejo Superior De Investigaciones Científicas ,  Servicio de Salud de Castilla-la Mancha (SESCAM)

发明人： GONZÁLEZ PÉREZ, María Teresa ,  CAMARERO DE DIEGO, Julio ,  PÉREZ GARCÍA, Lucas ,  RODRÍGUEZ FERNÁNDEZ, María Isabel ,  MIRANDA SORIANO, Rodolfo ,  PERNA, Paolo ,  MARTÍNEZ RAMÍREZ, Isidoro ,  GUERRERO SÁNCHEZ, Rubén ,  RODILLA GONZÁLEZ, Beatriz Loreto ,  ARCHÉ NÚÑEZ, Ana ,  VERA GARCÍA, Arturo ,  ENGER, Luiz Guilherme ,  FLAMENT, Stéphane ,  GUILLET, Bruno ,  LAM CHOK SING, Marc Ah-Liong ,  MECHIN, Laurence Liliane ,  ROUSSEAU, Olivier Henri Marc ,  BALLERINI, Laura ,  SCAINI, Denis ,  CALARESU, Ivo ,  SERRANO LÓPEZ-TERRADAS, María Concepción ,  DOMÍNGUEZ BAJO, Ana ,  LÓPEZ DOLADO, Elisa ,  GONZÁLEZ MAYORGA, Francisco Ankor ,  LEBARGY, Sylvain

IPC分类号： A61B5/00

摘要： The present invention relates to a probe, a monitoring device, a method for monitoring, the use of the monitoring device, a medical device A, a medical device B, methods for cell monitoring and stimulating, the use of medical device A and the use of medical device B.