专利检索 ap:("YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM" OR "THE HOSPITAL FOR SICK CHILDREN RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP") AND inv:"ROIFMAN, Chaim" 第 1 页

1.

发明公开
USE OF BENZYLIDENE-MALONONITRILE DERIVATES FOR THE TREATMENT OF LEUKEMIA 失效
标题翻译：使用亚苄基MALONONITRILDERIVATE用于治疗白血病

公开(公告)号：EP0754038A1

公开(公告)日：1997-01-22

申请号：EP95917619.0

申请日：1995-04-20

申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM , THE HOSPITAL FOR SICK CHILDREN RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP

发明人： LEVITZKI, Alexander , GAZIT, Aviv , ROIFMAN, Chaim

IPC分类号： A61K31

CPC分类号： A61K31/275

摘要： The present invention relates to products and methods useful for treating leukemia, in particular acute lymphoblastomic leukemias. Compounds described herein are effective in inhibiting activities associated with ALL both in vitro and in vivo. Methods for modifying such compounds and screening other compounds are also provided in order to identify additional compounds with similar or better inhibition properties.