公开(公告)号：EP2979702A4

公开(公告)日：2016-11-16

申请号：EP14775983

申请日：2014-02-10

申请人： ZERIA PHARM CO LTD ,  UNIV SAITAMA

发明人： SAKAI TAKAFUMI ,  SAKATA ICHIRO ,  KURODA KAYURI ,  YOSHIMURA MAKOTO

IPC分类号： A61K38/25 ,  A61K38/22 ,  A61K45/00 ,  A61K45/06 ,  A61P1/14

CPC分类号： A61K38/2214 ,  A61K9/0019 ,  A61K9/0053 ,  A61K38/22 ,  A61K38/25 ,  A61K45/06 ,  A61K2300/00

摘要： To provide a therapeutic agent for gastrointestinal disorder such as diabetic gastroparesis. A postprandial gastrokinetic agent containing (A) ghrelin or a ghrelin agonist and (B) motilin or a motilin agonist as active ingredients, in which both the ingredients (A) and (B) are administered so as to act on the stomach after food intake.

摘要翻译： 提供胃肠道疾病如糖尿病性胃轻瘫的治疗剂。 含有（A）生长素释放肽或生长素释放肽激动剂和（B）胃动素或胃动素激动剂作为活性成分的餐后胃动力剂，其中施用成分（A）和（B）以在食物摄取后作用于胃 。

公开(公告)号：EP2022851A4

公开(公告)日：2009-06-03

申请号：EP07743474

申请日：2007-05-16

申请人： MITSUBISHI GAS CHEMICAL CO ,  UNIV SAITAMA

发明人： IKEMOTO KAZUTO ,  OKUBO YUSUKE ,  KOIKE KANAKO ,  AIZAWA SAYAKA ,  SAKATA ICHIRO ,  SAKAI TAKAFUMI

IPC分类号： C12N15/00 ,  A61K48/00 ,  C12N5/10 ,  C12N15/09 ,  C12N15/87

CPC分类号： C12N15/87

摘要： [PROBLEMS] To provide a method whereby multiple kinds of substances for transferring into cells can be continuously transferred into multiple kinds of cells by a convenient procedure; a cell into which a substance for transferring into cells has been transferred by the above method; and an apparatus for transferring substances into cells by using the above method. [MEANS FOR SOLVING PROBLEMS] The above problems can be solved by electrospraying a liquid free from a substance for transferring into cells onto cells while the cells are in contact with substances for transferring into cells, or electrospraying a liquid free from a substance for transferring into cells onto cells and then bringing the cells into contact with the substances for transferring into cells.

摘要翻译： [问题]提供一种方法，通过方便的步骤可以将多种转移入细胞的物质连续转移到多种细胞中; 通过上述方法转移了转移到细胞中的物质的细胞; 以及使用上述方法将物质转移到细胞中的装置。 解决问题的手段上述问题可以通过以下方式来解决：在细胞与用于转移入细胞的物质接触的同时电喷射不含用于将细胞转移至细胞的物质的液体，或电喷射不含用于转移的物质的液体 细胞接触细胞，然后使细胞与物质接触以转移入细胞。