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1.发明公开METHOD FOR INJECTING DRUG INTO LIVING BODY BY ELECTROSPRAYING AND DEVICE THEREFOR 审中-公开方法ACTIVE注射到活体BY电喷及其装置
公开(公告)号：EP2388040A4
公开(公告)日：2013-12-25
申请号：EP10731212
申请日：2010-01-08
发明人： IKEMOTO KAZUTO , SAKAI TAKAFUMI , KOIKE KANAKO , SAKAHARA SATOSHI
CPC分类号： A61M5/30 , A61M2205/8206
摘要： The present invention provides a method whereby a drug can be conveniently injected into the living body, without sticking a needle, from a device that is not in contact with the living body, and a device therefor. Specifically provided is a method for injecting a peptide drug such as insulin, and a device therefor. No special consumables are needed except the drug solution or suspension. The method and device comprise injecting a drug into the living body by electrospraying a solution or suspension of the drug from a nozzle to which high voltage is applied and which is not in contact with the living body.
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2.发明公开
公开(公告)号：EP2022851A4
公开(公告)日：2009-06-03
申请号：EP07743474
申请日：2007-05-16
发明人： IKEMOTO KAZUTO , OKUBO YUSUKE , KOIKE KANAKO , AIZAWA SAYAKA , SAKATA ICHIRO , SAKAI TAKAFUMI
CPC分类号： C12N15/87
摘要： [PROBLEMS] To provide a method whereby multiple kinds of substances for transferring into cells can be continuously transferred into multiple kinds of cells by a convenient procedure; a cell into which a substance for transferring into cells has been transferred by the above method; and an apparatus for transferring substances into cells by using the above method. [MEANS FOR SOLVING PROBLEMS] The above problems can be solved by electrospraying a liquid free from a substance for transferring into cells onto cells while the cells are in contact with substances for transferring into cells, or electrospraying a liquid free from a substance for transferring into cells onto cells and then bringing the cells into contact with the substances for transferring into cells.
摘要翻译： [问题]提供一种方法，通过方便的步骤可以将多种转移入细胞的物质连续转移到多种细胞中; 通过上述方法转移了转移到细胞中的物质的细胞; 以及使用上述方法将物质转移到细胞中的装置。 解决问题的手段上述问题可以通过以下方式来解决：在细胞与用于转移入细胞的物质接触的同时电喷射不含用于将细胞转移至细胞的物质的液体，或电喷射不含用于转移的物质的液体 细胞接触细胞，然后使细胞与物质接触以转移入细胞。
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公开(公告)号：EP2455379A4
公开(公告)日：2012-10-24
申请号：EP10799695
申请日：2010-06-09
发明人： EDAHIRO JUNICHI , SAKAMOTO HITOSHI , IKEMOTO KAZUTO , SHIMIZU HAJIME , HASEGAWA TATSUYA , NAKANO MASAHIKO
IPC分类号： C07D471/04 , A23L1/30 , A61K31/4745 , A61P1/16 , A61P17/02 , A61P27/12 , A61P35/00 , A61P37/08 , A61P43/00
CPC分类号： C07D471/04 , A23L33/10 , A23L33/15 , A23V2002/00 , C07B2200/13
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4.发明公开
公开(公告)号：EP2722331A4
公开(公告)日：2014-11-05
申请号：EP12800143
申请日：2012-06-15
发明人： IKEMOTO KAZUTO , SAKAMOTO HITOSHI
IPC分类号： C07D471/04 , A61K31/4745 , A61P1/16 , A61P17/02 , A61P27/12 , A61P35/00 , A61P37/08 , A61P43/00 , C12P7/66
CPC分类号： C07D471/04 , C12P7/66
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公开(公告)号：EP3199154A4
公开(公告)日：2018-02-28
申请号：EP15843935
申请日：2015-09-18
发明人： MORI IKUE , SASAKURA HIROYUKI , IKEMOTO KAZUTO , NAKANO MASAHIKO
IPC分类号： A61K31/4745 , A61P43/00
CPC分类号： C07D471/04 , A61K31/4745
摘要： The present invention provides a life-extending agent comprising pyrroloquinoline quinone and/or a derivative of the pyrroloquinoline quinone.
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公开(公告)号：EP2497769A4
公开(公告)日：2013-05-01
申请号：EP10828355
申请日：2010-11-05
发明人： IKEMOTO KAZUTO , EDAHIRO JUNICHI
IPC分类号： C07D471/04
CPC分类号： C07D471/04
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公开(公告)号：EP2537848A4
公开(公告)日：2013-08-07
申请号：EP11744673
申请日：2011-02-16
发明人： IKEMOTO KAZUTO , NAKANO MASAHIKO , EDAHIRO JUNICHI
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： An object of the present invention is to provide a method for conveniently producing reduced pyrroloquinoline quinone from oxidized pyrroloquinoline quinone without needing expensive equipment, and a method for stabilizing reduced pyrroloquinoline quinone. According to the present invention, high-quality reduced pyrroloquinoline quinone can be obtained conveniently and efficiently in a manner suitable for industrial-scale production by mixing pyrroloquinoline quinone and ascorbic acid in a solvent.
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