PROCESS FOR PREPARING AN ACID RESISTANT CELLULOSE CAPSULE

    公开(公告)号:EP3698774A1

    公开(公告)日:2020-08-26

    申请号:EP20156545.4

    申请日:2020-02-11

    申请人: Suheung Co., Ltd

    发明人: YANG, Joo-Hwan

    摘要: The present invention relates to a process for preparing an acid resistant cellulose capsule. More specifically, this invention relates to a process for preparing an acid resistant cellulose capsule comprising the steps of: i) preparing 100 wt part of aqueous solution of solubilized cellulose including 15-25 wt part of cellulose; ii) sequentially adding and solubilizing 2.0-4.0 wt part of amid pectin and 0.1-1.0 wt part of iota-carrageenan as a gelling agent, an auxiliary gelling agent, a pH neutralizing agent, an emulsifying agent, a viscosity stabilizing agent and a plasticizing agent to the resulting admixture; and iii) allowing it to stand and to be equilibrated with adjustment of viscosity, before forming the capsule.

    PROCESS FOR MANUFACTURING PULLULAN HARD CAPSULES HAVING IMPROVED FILM PROPERTIES

    公开(公告)号:EP3479821A1

    公开(公告)日:2019-05-08

    申请号:EP18153754.9

    申请日:2018-01-26

    申请人: Suheung Co., Ltd

    发明人: YANG, Joo-Hwan

    IPC分类号: A61K9/48

    摘要: The present invention relates to a process for manufacturing pullulan hard capsules having improved film properties. More particularly, the present invention relates to a process for manufacturing pullulan hard capsules having improved film properties by solving the problems, such as, sticky among pullulan hard capsules, storage stability and/or brittleness.

    PROCESS FOR PREPARING HYPROMELLOSE HARD CAPSULE USING THERMOGELATION

    公开(公告)号:EP3513785A1

    公开(公告)日:2019-07-24

    申请号:EP18163408.0

    申请日:2018-03-22

    申请人: Suheung Co., Ltd.

    发明人: Yang, Joo-Hwan

    IPC分类号: A61K9/48 A61J3/07 A61K31/167

    摘要: The present invention relates to a process for preparing hypromellose hard capsule using thermogelation with improved storage stability, film strength, film distribution, filling up performance and/or bioavailability of ingredient. More specifically, this invention relates to a process for preparing hypromellose hard capsule using thermogelation with improved storage stability, film strength, film distribution, filling up performance and/or bioavailability of ingredient, comprising the steps of: i) sequentially adding and solubilizing 0.1-0.5 wt part of plasticizer, 0.1-0.5 wt part of wetting agent and a small amount of a viscosity stabilizer to the 100 wt part of hypromellose aqueous dispersion containing 19-22 wt part of hypromellose; ii) adjusting the viscosity of the mixture into 800-1,300 cP; iii) dipping the mold pin into the hypromellose aqueous solution maintained at 19-21 °C after preheating the mold pin to be 100-120 °C; and iv) forming the hypromellose hard capsule.

    MANUFACTURING METHOD FOR SOFTGEL CAPSULE CONTAINING SOLID AND LIQUID FORMULATIONS AS CORE INGREDIENT
    7.
    发明公开
    MANUFACTURING METHOD FOR SOFTGEL CAPSULE CONTAINING SOLID AND LIQUID FORMULATIONS AS CORE INGREDIENT 审中-公开
    HERSTELLUNGSVERFAHRENFÜRSOFTGELKAPSEL MIT FESTEN UNDFLÜSSIGENFORMULIERUNGEN ALS KERNBESTANDTEIL

    公开(公告)号:EP3141247A1

    公开(公告)日:2017-03-15

    申请号:EP15188232.1

    申请日:2015-10-02

    申请人: Suheung Co., Ltd

    IPC分类号: A61K9/48

    CPC分类号: A61K9/4808 A61K9/4833

    摘要: The present invention relates to a manufacturing method for softgel capsule containing solid and liquid formulations as core ingredient, wherein at least one pharmaceutical drug can be included in both solid formulation and liquid formulation. More particularly, this invention relates to a softgel capsule wherein liquid formulation, for example, solution and/or suspension as well as solid formulation, for example, tablet, pellet and/or sustained release dosage are present as core ingredient and its manufacturing method.

    摘要翻译: 本发明涉及含有固体和液体制剂作为核心成分的软胶囊的制备方法,其中至少一种药物可以包括在固体制剂和液体制剂中。 更具体地,本发明涉及一种软胶囊,其中液体制剂例如溶液和/或悬浮液以及固体制剂,例如片剂,丸剂和/或持续释放剂量作为核心成分及其制备方法存在。