公开(公告)号：EP4189113A1

公开(公告)日：2023-06-07

申请号：EP21762098.8

申请日：2021-07-29

申请人： Istituto Nazionale di Astrofisica ,  Universita'Degli Studi di Roma "La Sapienza" ,  Alma Mater Studiorum Universita di Bologna ,  UNIVERSITA' DEGLI STUDI DI MILANO ,  Politecnico di Milano

发明人： ESPOSITO, Francesca ,  BRUCATO, John Robert ,  COZZOLINO, Fabio ,  MONGELLUZZO, Giuseppe ,  POPA, Ciprian Ionut ,  FORNARO, Teresa ,  MENEGHIN, Andrea ,  PAGLIALUNGA, Daniele ,  PARESCHI, Giovanni ,  DE CESARE, Giampiero ,  CAPUTO, Domenico ,  NASCETTI, Augusto ,  COSTANTINI, Francesca ,  LOVECCHIO, Nicola ,  IANNASCOLI, Lorenzo ,  MIRASOLI, Mara ,  MICHELINI, Elisa ,  GUARDIGLI, Massimo ,  CLERICI, Mario ,  TRABATTONI, Daria ,  BIASIN, Mara ,  SCACCABAROZZI, Diego

IPC分类号： C12Q1/6806 ,  G01N1/22 ,  G01N1/24

公开(公告)号：EP4021637A1

公开(公告)日：2022-07-06

申请号：EP20761911.5

申请日：2020-08-25

申请人： Versalis S.p.A. ,  Alma Mater Studiorum Universita di Bologna

发明人： VELASQUEZ OCHOA, Juliana ,  CAVANI, Fabrizio ,  TOSI, Irene ,  FARCI, Erika ,  VECCHINI, Nicola

IPC分类号： B01J21/12 ,  B01J27/20 ,  B01J21/18 ,  B01J35/02 ,  B01J37/03 ,  B01J37/08 ,  C07C11/167 ,  C07C33/025 ,  B01J23/10

公开(公告)号：EP3930772A1

公开(公告)日：2022-01-05

申请号：EP20714706.7

申请日：2020-02-25

申请人： Alma Mater Studiorum Universita di Bologna ,  Universita' Cattolica Del Sacro Cuore

发明人： DI VITO, Maura ,  MATTARELLI, Paola ,  MODESTO, Monica ,  BUGLI, Francesca ,  MONDELLO, Francesca

IPC分类号： A61L15/40 ,  A61L15/44 ,  A61L15/60 ,  A61K36/752 ,  A61L15/34 ,  A61L15/46

公开(公告)号：EP3811433A1

公开(公告)日：2021-04-28

申请号：EP19737249.3

申请日：2019-06-19

申请人： Alma Mater Studiorum Universita di Bologna

发明人： ROSSI, Claudio ,  PILATI, Alessio ,  MARANO, Matteo

IPC分类号： H01M2/10 ,  H01M2/20 ,  H01M2/22 ,  H01M10/48 ,  H01M10/63 ,  H01M10/615 ,  H01M10/613 ,  H01M10/625

公开(公告)号：EP3727036A1

公开(公告)日：2020-10-28

申请号：EP18830313.5

申请日：2018-12-13

申请人： Alma Mater Studiorum Universita di Bologna ,  Oleificio Zucchi S.p.A.

发明人： DI LECCE, Giuseppe ,  ZUCCHI, Giovanni ,  BARBIERI, Sara ,  GALLINA TOSCHI, Tullia ,  MANDRIOLI, Mara ,  VALLI, Enrico ,  SGARZI, Federica ,  SERRA, Valentina ,  MERLI, Fausto

IPC分类号： A23L33/105 ,  A23D9/007 ,  A61K36/9066

公开(公告)号：EP2739992B1

公开(公告)日：2015-10-14

申请号：EP11757940.9

申请日：2011-08-02

申请人： Alma Mater Studiorum -Universita' di Bologna ,  Elettra - Sincrotrone Trieste S.C.P.A.

发明人： FRABONI, Beatrice ,  FRALEONI MORGERA, Alessandro

IPC分类号： G01T1/24

CPC分类号： H01L51/441 ,  G01T1/24 ,  H01L51/0003 ,  H01L51/0067

公开(公告)号：EP2880015A1

公开(公告)日：2015-06-10

申请号：EP13755978.7

申请日：2013-08-01

申请人： Fondazione Istituto Italiano Di Tecnologia ,  The Regents of the University of California ,  Alma Mater Studiorum -Universita' di Bologna

发明人： DE VIVO, Marco ,  SCARPELLI, Rita ,  CAVALLI, Andrea ,  MIGLIORE, Marco ,  PIOMELLI, Daniele ,  HABRANT, Damien ,  FAVIA, Angelo

IPC分类号： C07C271/28 ,  C07C271/42 ,  C07C271/44 ,  C07C271/56 ,  C07C271/58 ,  A61K31/325 ,  A61P35/00

CPC分类号： C07C271/56 ,  C07C271/28 ,  C07C271/44 ,  C07C271/58 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14

摘要： The invention provides novel multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. The invention concerns also with therapeutical application of the multitarget inhibitors in particular in the prevention and treatment of cancer.

摘要翻译： 脂肪酸酰胺水解酶（FAAH），环氧合酶-1（COX-1）和/或环氧合酶-2（COX-2）的多靶抑制剂在取代的A环的间位或邻位上具有特定的氨基甲酸酯部分 联苯核心，在联苯核心的B环的邻位具有卤素。 还涉及多靶抑制剂的治疗应用，特别是预防和治疗癌症。

公开(公告)号：EP2684195B1

公开(公告)日：2015-01-07

申请号：EP12706869.0

申请日：2012-03-06

申请人： CNR - Consiglio Nazionale Delle Ricerche ,  Alma Mater Studiorum -Universita' di Bologna

发明人： BONFIGLIO, Annalisa ,  FRABONI, Beatrice ,  MATTANA, Giorgio

IPC分类号： H01B1/00

CPC分类号： H01B1/22 ,  H01B1/00 ,  H01B13/0036 ,  H01L51/0558 ,  Y10T428/2944 ,  Y10T428/2949

公开(公告)号：EP2815249A1

公开(公告)日：2014-12-24

申请号：EP13713538.0

申请日：2013-02-14

申请人： Alma Mater Studiorum -Universita' di Bologna

发明人： DARDARI, Davide ,  DECARLI, Nicolò

IPC分类号： G01S5/14 ,  G01S11/06 ,  H04B5/00

CPC分类号： G01S5/14 ,  G01S11/06 ,  H04B5/00

摘要： A method for estimating a distance (d) of a transmitting device (2; 2a) from at least one receiving device (3; 3a; 3b) comprises the following steps: - generating with said transmitting device (2; 2a) a first sinusoidal signal at a first frequency f1; - generating with said transmitting device (2; 2a) a second sinusoidal signal at a second frequency f2, synchronized with the first sinusoidal signal; - transmitting said first sinusoidal signal and said second sinusoidal signal at the receiving device (3, 3a, 3b); - estimating the phase of said first sinusoidal signal and said second sinusoidal signal received by said receiving device (3; 3 a; 3b); - estimating said distance (d) on the basis of said the phase estimation of the first sinusoidal signal and said second sinusoidal signals. A localization system that comprises a transmitting device (2) and at least 3 receiving devices (3; 3a; 3b), placed in known positions, and is capable of estimating the position (p) of said transmitting device (2) with respect to the receiving devices (3; 3a; 3b).

公开(公告)号：EP2804615A1

公开(公告)日：2014-11-26

申请号：EP13700757.1

申请日：2013-01-21

申请人： ISTITUTO SUPERIORE DI SANITA ,  Alma Mater Studiorum -Universita' di Bologna

发明人： FIORENTINI, Carla ,  LOIZZO, Stefano ,  MALCHIODI-ALBEDI, Fiorella ,  TRAVAGLIONE, Sara ,  RIMONDINI, Roberto ,  CAMPANA, Gabriele

IPC分类号： A61K38/16 ,  A61P25/28 ,  A61P25/16 ,  A61P27/06

CPC分类号： A61K38/164

摘要： Cytotoxic necrotising factor 1 (CNF1) treats dysfunctional astrocytes and is useful to treat conditions associated with astrogliosis and/or neuroinflammation.