公开(公告)号：EP2814592A1

公开(公告)日：2014-12-24

申请号：EP13703200.9

申请日：2013-01-18

申请人： Saudi Arabian Oil Company ,  Research Triangle Institute

发明人： HAMAD, Esam, Zaki ,  AL-SADAT, Wajdi, Issam ,  COLEMAN, Luke ,  SHEN, J.P. ,  GUPTA, Raghubir

IPC分类号： B01D53/02 ,  B01D53/62 ,  B01D53/92 ,  B01J20/04

CPC分类号： B01D53/94 ,  B01D53/02 ,  B01D53/62 ,  B01D53/82 ,  B01D53/92 ,  B01D2251/30 ,  B01D2251/302 ,  B01D2251/304 ,  B01D2251/306 ,  B01D2251/402 ,  B01D2251/60 ,  B01D2251/602 ,  B01D2251/606 ,  B01D2253/112 ,  B01D2253/1124 ,  B01D2257/504 ,  B01D2258/012 ,  B01D2259/4566 ,  B01J20/04 ,  B01J20/041 ,  B01J20/043 ,  B01J20/3085 ,  B01J20/3433 ,  B01J20/3483 ,  B01J2220/42 ,  Y02A50/2342 ,  Y02C10/04 ,  Y02C10/08

摘要： The invention relates to a mixed salt composition which is useful as a CO2 sorbent. The mixed salt composition comprises a Mg salt, and at least one Group IA element salt, where the Mg and Group IA element are present at a molar ratio of from 3:1 to 8:1. The resulting composition can adsorb about 20% or more of CO2 in a gas. Via varying the molar ratios of the components, and the Group IA element, one can develop compositions which show optional functionality at different conditions. The composition is especially useful in the adsorptive capture of CO2 on mobile sources, such as transportation vehicles, where it can be recovered during regeneration of the adsorbent composition and the CO2 used as a coolant gas, as a reactant in manufacture of fuel, and so forth.

公开(公告)号：EP2788359A1

公开(公告)日：2014-10-15

申请号：EP12854821.1

申请日：2012-12-06

申请人： Research Triangle Institute

发明人： RUNYON, Scott ,  ZHANG, Yanan ,  HASSLER, Carla ,  GILMOUR, Brian

IPC分类号： C07D491/04 ,  A61K31/4355 ,  A61P25/00

CPC分类号： C07D491/048 ,  C07D491/04 ,  C07D491/10 ,  C07D491/107

摘要： Neuropeptide S receptor antagonists are provided that bind in functional assays to neuropeptide S receptors; methods are provided for use of these antagonists in treatment of conditions or disease states that are ameliorated by blocking of the neuropeptide S receptor, including substance abuse and substance abuse relapse; and for use of neuropeptide S receptor antagonists in the manufacture of therapeutics and pro-drugs for therapeutics useful in disease states and conditions sensitive to binding of the neuropeptide S receptor.

公开(公告)号：EP2788119A1

公开(公告)日：2014-10-15

申请号：EP12799489.5

申请日：2012-12-04

申请人： Research Triangle Institute ,  The University of North Carolina at Chapel Hill

发明人： GREGO, Sonia ,  GILCHRIST, Kristin Hedgepath ,  RANDELL, Scott H.

IPC分类号： B01L3/00 ,  C12M3/06 ,  G01N33/50

CPC分类号： G09B23/306 ,  C12M21/08 ,  C12M23/16 ,  C12M25/02 ,  C12M25/14 ,  C12M35/08 ,  G01N33/5088

摘要： A multicellular fluidic enhanced airway model system of the conducting airways as a tool for the evaluation of biological threats and medical countermeasures is provided. The airway model system can include a first chamber having an inlet and an outlet and containing epithelial cells; a second chamber having an inlet and an outlet and containing an extracellular matrix, wherein the second chamber is separated from the first chamber by a porous membrane; and a third chamber having an inlet and an outlet, wherein the third chamber is separated from the second chamber by a porous membrane, and wherein the airway tissue model system is configured to provide a separate fluidic pathway through each of said first, second, and third chambers. A method of analyzing tissue response to an agent via an airway tissue model system is also provided.

公开(公告)号：EP2773352A2

公开(公告)日：2014-09-10

申请号：EP12856118.0

申请日：2012-12-10

申请人： Research Triangle Institute, International

发明人： CARROLL, Frank, I. ,  THOMAS, James, B. ,  NAVARRO, Hernan, A. ,  MASCARELLA, S., Wayne ,  RUNYON, Scott, P. ,  JIN, Chunyang ,  KORMOS, Chad, M.

IPC分类号： A61K31/496

CPC分类号： C07D401/12 ,  C07D241/04 ,  C07D295/13

摘要： Provided are compounds represented by the formula: where R, Y
3 , R
1 ,
R
2 , R
3 , R
4 , R
6 , G, R
7 , E
1 , E
2 , A, B, W, X, Y and Z are as defined herein.

摘要翻译： 提供了由下式表示的化合物：其中R，Y3，R1，R2，R3，R4，R6，G，R7，E1，E2，A，B，W，X，Y和Z如本文所定义。

公开(公告)号：EP2663381A2

公开(公告)日：2013-11-20

申请号：EP11808761.8

申请日：2011-12-16

申请人： Research Triangle Institute

发明人： JAMAL, Aqil ,  GUPTA, Raghubir P.

IPC分类号： B01D53/04 ,  B01D53/62

CPC分类号： F02M25/07 ,  B01D53/04 ,  B01D53/62 ,  B01D2251/304 ,  B01D2251/606 ,  B01D2257/504 ,  B01D2258/0283 ,  B01D2259/40088 ,  F02M26/00 ,  Y02A50/2342 ,  Y02C10/04 ,  Y02C10/08

摘要： The present invention provides a method of increasing the efficiency of exothermic CO2 capture processes. The method relates to withdrawing heat generated during the exothermic capture of CO2 with various sorbents via heat exchange with a working fluid. The working fluid is provided at a temperature and pressure such that it is in the liquid state, and has a vaporization temperature in a range such that the heat arising from the reaction of the CO2 and the sorbent causes a phase change from liquid to vapor state in whole or in part and transfers heat from to the working fluid. The resulting heated working fluid may subsequently be used to generate power.

公开(公告)号：EP2646172A2

公开(公告)日：2013-10-09

申请号：EP11801909.0

申请日：2011-11-30

申请人： Research Triangle Institute

发明人： DAUSCH, David ,  CARLSON, James ,  GILCHRIST, Kristin Hedgepath

IPC分类号： B06B1/06 ,  A61B8/12

CPC分类号： A61B8/4494 ,  A61B8/12 ,  A61B8/445 ,  A61N7/00 ,  B06B1/0622 ,  Y10T29/42

摘要： A method and apparatus directed to formation of a connection with an ultrasonic transducer apparatus (UTA) comprising a transducer device having first and second electrodes is provided. The UTA is engaged with an interposer device surface. The interposer device is greater in at least one lateral dimension than and extends laterally outward of the UTA, and comprises at least two laterally-extending conductors. A conductive engagement is formed between the first and second electrodes and respective first ends of the conductors. A connection support substrate is engaged with the interposer device about second ends of the conductors, and includes at least two connective elements for forming a conductive engagement with the respective second ends of the conductors. The UTA is then inserted into a catheter member lumen such that the device plane of the UTA and the at least two connective elements extend axially along the lumen.

公开(公告)号：EP2611518A1

公开(公告)日：2013-07-10

申请号：EP11758030.8

申请日：2011-09-02

申请人： Research Triangle Institute

发明人： LAIL, Marty ,  COLEMAN, Luke

IPC分类号： B01D53/14

CPC分类号： B01D53/40 ,  B01D53/1425 ,  B01D53/1456 ,  B01D53/1475 ,  B01D53/1493 ,  B01D2252/202 ,  B01D2252/20405 ,  B01D2252/20421 ,  B01D2252/20426 ,  B01D2252/504 ,  B01D2257/30 ,  B01D2257/302 ,  B01D2257/308 ,  B01D2257/404 ,  B01D2257/504 ,  B01D2258/0283 ,  Y02A50/2342 ,  Y02C10/06

摘要： A solvent system comprising a diluent and a nitrogenous base for the removal of CO 2 from mixed gas streams is provided. Also provided is a process for removing CO 2 from mixed gas streams using the disclosed solvent system. The solvent system may be utilized within a gas processing system.

摘要翻译： 提供了一种包含用于从混合气流中除去CO 2的稀释剂和含氮碱的溶剂体系。 还提供了使用所公开的溶剂系统从混合气流中除去CO 2的方法。 溶剂系统可以在气体处理系统中使用。

公开(公告)号：EP2563124A1

公开(公告)日：2013-03-06

申请号：EP10844099.1

申请日：2010-01-19

申请人： Research Triangle Institute

发明人： Carroll, Frank, Ivy ,  Thomas, James, B. ,  Mascarella, Wayne, S.

IPC分类号： A01N43/40

CPC分类号： A61K31/4725 ,  A61K45/06 ,  C07D401/12

摘要： Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor, such as heroin or cocaine addictions.

摘要翻译： 提供了κ阿片受体拮抗剂，其在对κ阿片受体的功能结合测定中产生显着改善，并且使用这些拮抗剂治疗通过结合κ阿片受体如海洛因或可卡因成瘾而改善的疾病状态。

公开(公告)号：EP2039701A3

公开(公告)日：2013-02-27

申请号：EP08101671.9

申请日：1999-03-05

申请人： RESEARCH TRIANGLE INSTITUTE

发明人： Cook, Edgar, C. ,  Kepler, John, A. ,  Zhang, Ping-sheng ,  Lee, Yue-wei ,  Tallent, Ray, C.

IPC分类号： C07J33/00 ,  C07J43/00 ,  A61K31/58 ,  A61P5/36 ,  C07J41/00

CPC分类号： C07J41/0083 ,  A61K31/58 ,  C07J43/006 ,  Y10S514/841 ,  Y10S514/843

摘要： The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.

公开(公告)号：EP2483926A1

公开(公告)日：2012-08-08

申请号：EP10771834.8

申请日：2010-09-29

申请人： Research Triangle Institute, International

发明人： KLEM, Ethan ,  LEWIS, John

IPC分类号： H01L27/30 ,  H01L51/42 ,  H01L51/05 ,  H01L51/00

CPC分类号： H01L27/305 ,  B82Y10/00 ,  H01L51/0046 ,  H01L51/0545 ,  H01L51/0562 ,  H01L51/4213 ,  H01L51/422 ,  H01L2251/305 ,  Y02E10/549

摘要： An optoelectronic device includes a first electrode, a quantum dot layer disposed on the first electrode including a plurality of quantum dots, a fullerene layer disposed directly on the quantum dot layer wherein the quantum dot layer and the fullerene layer form an electronic heterojunction, and a second electrode disposed on the fullerene layer. The device may include an electron blocking layer. The quantum dot layer may be modified by a chemical treatment to exhibit increased charge carrier mobility.

摘要翻译： 光电子器件包括第一电极，设置在包括多个量子点的第一电极上的量子点层，直接设置在量子点层上的富勒烯层，其中量子点层和富勒烯层形成电子异质结，以及 设置在富勒烯层上的第二电极。 该器件可以包括电子阻挡层。 量子点层可以通过化学处理来改变以显示出增加的电荷载流子迁移率。