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公开(公告)号:EP2926323B1
公开(公告)日:2022-12-14
申请号:EP13783302.6
申请日:2013-10-23
发明人: OSYRA, Siegmund
IPC分类号: G07D7/202 , G06V10/147
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公开(公告)号:EP4092631A1
公开(公告)日:2022-11-23
申请号:EP22173562.4
申请日:2022-05-16
IPC分类号: G06V10/145 , G06V10/147 , G06V10/82 , G06V20/69
摘要: A method and system are provided for illuminating and imaging a biological sample using a brightfield microscope for the purpose of counting biological cells. The method comprises the steps of, by a processing device: a. positioning a sample to be viewed by way of an objective lens of the microscope, and on an x-y plane at an x-y position of a plurality of x-y positions, the sample comprising a plurality of biological cells; b. capturing and storing, using an image capturing apparatus, one or more focal image stacks, each said focal image stack comprising a plurality of focal images of the sample positioned at the x-y position, each of the focal images in the focal image stack being captured at a different focal position of a plurality of discrete focal positions within a focal range, the focal range being located on a z plane perpendicular to the x-y plane; c. processing the one or more focal image stacks using a cell localisation neural network, the cell localisation neural network outputting a list of one or more cell locations, each said cell location corresponding to a cell characteristic determined by the cell localisation neural network; d. determining, using the list of cell locations, one or more cell focal image stacks, each cell focal image stack being obtained from the one or more focal image stacks; and e. processing the one or more cell focal image stacks using an encoder neural network, the encoder neural network outputting a list of cell fingerprints, each said cell fingerprint corresponding to a cell of the plurality of biological cells; f. determining, using the list of cell locations and the list of cell fingerprints, a number of cells within the sample. The present disclosure aims to provide a quick, non-invasive and reliable mode of counting biological cells.
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公开(公告)号:EP4040212A1
公开(公告)日:2022-08-10
申请号:EP21213915.8
申请日:2020-02-06
发明人: SHARMA, Robin , HATZILIAS, Karol Constantine , ZHANG, Qi , LIAO, Christopher Yuan, Ting , MALHOTRA, Tanya , ANDREEV, Gregory, Olegovic , SCHELLER, Maik , YE, Sheng , OUDERKIRK, Andrew, John , WEI, Guohua
IPC分类号: G02B19/00 , F21K9/60 , F21V5/04 , G02B3/08 , G02B1/00 , G02B3/00 , G06V10/147 , G06V40/19 , H01S5/00 , H01S5/183 , H01S5/343 , G02B27/09
摘要: An example device may include a light source, an optical element, and, optionally, an encapsulant layer. A light beam generated by the light source may be received by the optical element and redirected towards an illumination target, such as an eye of a user. The optical element may include a material, for example, with a refractive index of at least approximately 2 at a wavelength of the light beam. The light source may be a semiconductor light source, such as a light-emitting diode or a laser. The optical element may be supported by an emissive surface of the light source. Refraction at an exit surface of the optical element, and/or within a metamaterial layer, may advantageously modify the beam properties, for example, in relation to illuminating a target. In some examples, the light source and optical element may be integrated into a monolithic light source module.
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94.
公开(公告)号:EP3813355B1
公开(公告)日:2022-07-06
申请号:EP20198809.4
申请日:2020-09-28
发明人: Müller, Romain , Schneider, Florian
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公开(公告)号:EP3623921B1
公开(公告)日:2022-06-22
申请号:EP18913995.9
申请日:2018-08-02
发明人: GUO, Yiping
IPC分类号: G06V40/13 , G06F3/042 , G06V10/147
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