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    PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES
    102.
    发明公开
    PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES 失效
    VERFAHREN ZUR HERSTELLUNG VON ISOTHIAZOL-DERIVATEN

    公开(公告)号：EP0805151A1

    公开(公告)日：1997-11-05

    申请号：EP95938651.7

    申请日：1995-12-04

    申请人： SUMITOMO SEIKA CHEMICALS CO., LTD.

    发明人： KAGANO, Hirokazu Sumitomo Seika Chemicals Co. Ltd. ,  GODA, Hiroshi Sumitomo Seika Chemicals Co., Ltd. ,  YAMAMOTO, Mikio Sumitomo Seika Chemicals Co., Ltd. ,  SAKAUE, Shigeki Sumitomo Seika Chemicals Co., Ltd. ,  TOUDOU, Miki Sumitomo Seika Chemicals Co., Ltd.

    IPC分类号： C07D275/04

    CPC分类号： C07D275/04

    摘要： A method for producing a 1,2-benzisothiazole characterized by treating a 2-(alkylthio)benzaldehyde oxime with a halogen compound; a method for producing a 3-halo-1,2-benzisothiazole characterized by treating a 1,2-benzisothiazole with a halogenating agent; and a method for producing a 1-(1,2-benzisothiazol-3-yl)piperazine characterized by reacting the obtained 3-halo-1,2-benzisothiazoles with a piperazine. By the method of the present invention, 1,2-benzisothiazoles and 3-halo-1,2-benzisothiazoles, which are useful as intermediates for pharmaceutical compositions such as psychotropic agents, and 1-(1,2-benzisothiazole-3-yl)piperazines synthesized therefrom can be obtained in a high yield without using expensive starting materials by shorter and simpler process than conventional methods.

    摘要翻译： 一种1,2-苯并异噻唑的制备方法，其特征在于用卤素化合物处理2-（烷硫基）苯甲醛肟; 其特征在于用卤化剂处理1,2-苯并异噻唑的3-卤代-1,2-苯并异噻唑的制备方法。 以及1-（1,2-苯并异噻唑-3-基）哌嗪的制造方法，其特征在于使得到的3-卤代-1,2-苯并异噻唑与哌嗪反应。 通过本发明的方法，1,2-苯并异噻唑和3-卤代-1,2-苯并异噻唑可用作药物组合物如精神药物的中间体和1-（1,2-苯并异噻唑-3-基 ）哌嗪可以通过比常规方法更短和更简单的方法以高产率获得而不使用昂贵的起始原料。

    Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it
    105.
    发明公开
    Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it 失效
    氰基苯基硫基 - 卤化物和硫酸盐Verwendung在Verfahren zur Herstellung von 3-substitutioniertem Benzoisothiazol

    公开(公告)号：EP0741129A2

    公开(公告)日：1996-11-06

    申请号：EP96302851.9

    申请日：1996-04-24

    申请人： SUMITOMO SEIKA CHEMICALS CO., LTD.

    发明人： Goda, Hiroshi ,  Sakamoto, Junichi ,  Sakaue, Shigeki ,  Kajihara, Sakae ,  Todo, Miki

    IPC分类号： C07C313/16 ,  C07D275/04

    CPC分类号： C07D275/04 ,  C07C313/08 ,  C07C313/16

    摘要： A 2-cyanobenzenesulphenyl compound is represented by the general formula (I):

    wherein X represents Cl or Br and can be used for the preparation of 3-substituted benzisothiazole by reaction of the compound (I) with a piperazine compound. The compound (I) can be prepared by halogenating a 2-cyanophenylthio derivative of the formula (II):

    wherein R represents H, alkali metal, 2-cyanophenylthio or C 1-4 alkyl.

    摘要翻译： 2-氰基苯磺酰化合物由通式（I）表示：其中X表示Cl或Br，可用于通过化合物（I）与哌嗪化合物的反应制备3-取代的苯并异噻唑。 化合物（I）可以通过卤化式（II）的2-氰基苯硫基衍生物：其中R表示H，碱金属，2-氰基苯硫基或C 1-4烷基的来制备。

    PROCESS FOR PRODUCING HYDROGENATED NBR LATEX
    108.
    发明公开
    PROCESS FOR PRODUCING HYDROGENATED NBR LATEX 失效
    VERFAHREN ZUR HERSTELLUNG EINES HYDROGENIERTEN NBR-LATEX。

    公开(公告)号：EP0680992A1

    公开(公告)日：1995-11-08

    申请号：EP95900923.4

    申请日：1994-11-21

    申请人： SUMITOMO SEIKA CHEMICALS CO., LTD.

    发明人： ARAKI, Eiichi ,  SUGIHARA, Norihiro ,  KAMADA, Mari ,  MATSUKAWA, Taiji

    IPC分类号： C08J3/07

    CPC分类号： C08C19/02 ,  C08J3/07 ,  C08J2309/02

    摘要： A process for producing a hydrogenated NBR latex wherein the latex particles have each a sufficiently small diameter and which has a sufficient quiescence stability without using any harmful solvent and restricting the type of the emulsifying agent. The production process comprises mixing an organic phase containing hydrogenated NBR dissolved in an organic solvent with an aqueous phase containing an emulsifying agent dissolved in water to effect emulsification and then distilling off the solvent, and is characterized by effecting the emulsification in the presence of an alcohol.

    摘要翻译： 一种制备氢化NBR胶乳的方法，其中胶乳颗粒各自具有足够小的直径，并且具有足够的静止稳定性，而不使用任何有害溶剂并限制乳化剂的类型。 制备方法包括将溶解在有机溶剂中的含有氢化NBR的有机相与含有溶解在水中的乳化剂的水相混合以进行乳化，然后蒸除溶剂，其特征在于在醇存在下进行乳化 。