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121.发明公开METHOD OF DETECTING VERY LOW LEVELS OF ANALYTE WITHIN A THIN FILM FLUID SAMPLE CONTAINED IN A THIN THICKNESS CHAMBER 有权方法检测非常低的分析物水平在薄膜室含有薄膜流体样品
公开(公告)号：EP2281197A1
公开(公告)日：2011-02-09
申请号：EP09730905.8
申请日：2009-04-02
IPC分类号： G01N33/543 , G01N33/58
CPC分类号： G01N33/588 , B82Y15/00 , G01N33/54366
摘要： A method and apparatus for the detection and quantification of very low levels of a target analyte using an imaging system is provided. In the case of some analytes such as certain hormones, for example TSH, their levels may be as low as several tens of thousands of molecules per micro liter. These extremely low levels can be measured by using the present invention to count the individual molecules of analyte. The invention also has the advantage of being a primary quantitative method, which is one which needs no standardization.
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122.发明公开VIRTUAL SEPARATION OF BOUND AND FREE LABEL IN A LIGAND ASSAY FOR PERFORMING IMMUNOASSAYS OF BIOLOGICAL FLUIDS, INCLUDING WHOLE BLOOD 有权结合和游离的商标在配体测试程序虚拟分离免疫测试程序与对生物液体的执行情况，包括全血
公开(公告)号：EP2274612A1
公开(公告)日：2011-01-19
申请号：EP09727858.4
申请日：2009-04-02
IPC分类号： G01N33/543 , B01L3/00
CPC分类号： G01N33/48 , G01N21/6428 , G01N33/5304 , G01N33/54373 , G01N33/54386
摘要： Detection and characterization of immunologically detected substances are performed electronically on human and animal biological fluids such as whole blood, serum, plasma, urine, milk, pleural and peritoneal fluids, and semen, which fluids are contained in a thin chamber forming a quiescent fluid sample, which chamber has at least two parallel planar walls, at least one of which is transparent.
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123.发明公开
公开(公告)号：EP3707495A1
公开(公告)日：2020-09-16
申请号：EP18770085.1
申请日：2018-08-17
IPC分类号： G01N21/31 , B01L3/00 , G01N27/07 , G01N27/327
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公开(公告)号：EP3669173A1
公开(公告)日：2020-06-24
申请号：EP18769493.0
申请日：2018-08-17
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126.发明公开
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公开(公告)号：EP3489644A1
公开(公告)日：2019-05-29
申请号：EP18248240.6
申请日：2014-02-19
发明人： HOLT, Richard , MEHTA, Manav
IPC分类号： G01J3/51 , B01J19/00 , G01N21/64 , G01N33/543 , G01N21/03 , G01N33/49 , G01N35/00 , B01L3/00
摘要： A biological fluid sample analysis chamber (10) and a method for analyzing a biological fluid sample is provided. The chamber (10) includes a first chamber panel (12), a second chamber panel (14), and a plurality of beads (16) disposed between the first chamber panel and the second chamber panel, which beads are configured to not reflect light incident to the beads in an amount that appreciably interferes with a photometric analysis of the biologic fluid.
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公开(公告)号：EP2932260B1
公开(公告)日：2019-05-01
申请号：EP13815274.9
申请日：2013-12-06
发明人： VANDERSLEEN, Gary , EMERIC, Pierre , WASSERMAN, Paul , SOMAN, Narendra , DAVIS, Graham , FETTERS, Christopher
IPC分类号： G01N33/487
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129.发明公开
公开(公告)号：EP3351305A1
公开(公告)日：2018-07-25
申请号：EP18155417.1
申请日：2011-12-08
发明人： LALPURIA, Niten V. , UNFRICHT, Darryn W. , NIKONOROV, Igor , PORTS, Benjamin , OLSON, Douglas R.
CPC分类号： B01L3/5027 , B01F11/0071 , B01F13/0059 , B01L3/502707 , B01L2200/14 , B01L2300/0816 , B01L2300/161 , B01L2300/165 , G01N15/1463 , G01N15/1484 , G01N21/0303 , G01N21/05 , G01N33/48 , G01N33/487 , Y10T436/2575
摘要： An apparatus and method for analysing a biological fluid sample is provided. The method includes the steps of: a) providing an analysis cartridge having a channel and an analysis chamber, wherein the channel is in fluid communication with the analysis chamber and includes at least one hydrophobic interior wall surface; b) ad-mixing one or more anti-adsorption agents with fluid sample disposed within the channel, wherein the anti-adsorption agents are operable to inhibit adsorption of fluid sample onto the interior wall surface of the channel; c) moving the fluid sample into the analysis chamber; and d) analysing the sample within the analysis chamber.
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130.发明授权TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS 有权TSH免疫测定和在限制性洗涤格式中存在内源性污染物时进行TSH免疫测定的过程
公开(公告)号：EP2715368B1
公开(公告)日：2018-02-14
申请号：EP11793964.5
申请日：2011-11-29
IPC分类号： G01N33/577 , G01N33/53 , G01N33/76 , G01N33/543
CPC分类号： G01N33/76 , B01L3/50273 , B01L3/502738 , C07K16/26 , C07K2317/33 , G01N33/5302 , G01N33/543 , G01N33/74 , G01N2333/59
摘要： The invention relates to low wash Thyroid Stimulating Hormone (TSH) immunoassays using an ELISA sandwich assay having limited or no wash step between the antigen capture, detection antibody addition and substrate introduction steps. This invention exhibits low cross reactivity with biologically similar interfering cross reacting species, such as Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG).
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