公开(公告)号：EP2696773A1

公开(公告)日：2014-02-19

申请号：EP12715800.4

申请日：2012-04-12

申请人： St. Jude Medical, Inc.

发明人： SLIWA, John ,  NGUYEN, Tho Hoang ,  MA, Zhenyi ,  MORSE, Stephen

IPC分类号： A61B8/12 ,  A61B18/14

CPC分类号： A61B8/0858 ,  A61B8/12 ,  A61B8/445 ,  A61B8/5223 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00738 ,  A61B2034/303 ,  A61B2090/3784

摘要： A system for ablation with acoustic feedback comprises: a catheter (102) which includes an elongated catheter body; at least one ablation element to ablate a targeted tissue region; and a pulse-echo ultrasonic transducer (111) arranged to emit and receive an acoustic beam along a centroid in a beam direction, at a transducer beam angle (ϒ) of between about 30 degrees and about 60 degrees relative to a distal direction of the longitudinal axis at a location of intersection between the longitudinal axis and the beam direction of the centroid of the acoustic beam of the ultrasonic transducer, wherein the transducer transmits and receives acoustic pulses to provide lesion information in the targeted tissue region; an ablation power subsystem (105); an ultrasonic transmit and receive subsystem (106) to operate the ultrasonic transducer; a control subsystem (104) to control operation of the ablation power subsystem and the ultrasonic transmit and receive subsystem; and a display (107).

摘要翻译： 用于具有声反馈的消融系统包括：导管，其包括细长的导管体; 至少一个消融元件以消融靶向组织区域; 以及脉冲回波超声波换能器，其被布置成沿着波束方向沿着质心发射和接收声束，相对于纵向轴线的远端方向在约30度至约60度之间的换能器射束角处，位于 所述超声波换能器的所述声束的质心的纵轴与所述束方向之间的交点，其中所述换能器发射和接收声脉冲以在所述目标组织区域中提供病变信息; 消融电源子系统; 超声波发射和接收子系统来操作超声换能器; 用于控制消融电源子系统和超声波发射和接收子系统的操作的控制子系统; 和显示器。

公开(公告)号：EP2696747A1

公开(公告)日：2014-02-19

申请号：EP12719832.3

申请日：2012-04-13

申请人： St. Jude Medical, Inc.

发明人： SLIWA, John ,  LIU, Yu

IPC分类号： A61B5/00 ,  A61B5/02 ,  A61M25/00

CPC分类号： A61B5/0066 ,  A61B5/0053 ,  A61B5/02007 ,  A61B8/485 ,  A61M25/007 ,  A61M25/0082 ,  A61M29/02

摘要： An optical coherence tomography (OCT) catheter, for performing high performance elastographic deformation mapping of tissues and plaques, comprises: a catheter (20) having an elongated catheter body extending longitudinally between a proximal end and a distal end along a longitudinal axis, the catheter body including a distal portion (24) at the distal end and a catheter lumen (26); a palpator (30), disposed in the distal portion, to apply one of a directed fluid or a mechanical indenter (130) to produce a surface - applied palpation force to a target area (50) of the interior body to mechanically displace the interior body and cause elastographic deformation of the target area of one or more surface and subsurface tissues and plaques; and an OCT imaging sensor (34), disposed in the distal portion, to direct and deliver an OCT beam (60) for OCT deformation detection including elastographic deformation measurement to provide elastographic mapping of the target area.

摘要翻译： 一种用于执行组织和斑块的弹性成像形变映射方法包括：将导管的远端部分到患者的内部主体的内部; 施加，从在远端部分的palpator，的一个引导流体或机械压头，以产生表面施加的触诊力到内部身体的目标区域以机械地移动所述内部主体和造成的所述目标区域的弹性成像变形 一种或多种表面和表面下的组织和斑块; 和引导，并在远端部分递送（光学相干断层成像）波束华侨城，从在OCT成像传感器，华侨城变形检测包含弹性成像变形测量，以提供目标区域的弹性图映射。

公开(公告)号：EP2683288A2

公开(公告)日：2014-01-15

申请号：EP12709745.9

申请日：2012-03-02

申请人： St. Jude Medical, Inc.

发明人： LIU, Yu

IPC分类号： A61B5/00

CPC分类号： A61B5/0066 ,  G01B9/02004 ,  G01B9/02027 ,  G01B9/0205 ,  G01B9/02057 ,  G01B9/02069 ,  G01B9/02091 ,  G01B2290/45

摘要： A signal interrogation system comprises an optical coupler (22) to split input laser beam into a first laser beam as a power reference and a second laser beam, the optical coupler being coupled to a first path (24) for the first laser beam and a second path (25) for the second laser beam; an optical circulator (28) disposed in the second path; a bi-directional optical switch (30) disposed in the second path and having on one side a single channel end oriented toward the optical circulator and on another side multiple channel ends with multiple switchable channels; a plurality of optical fibers (34) coupled to the multiple channel ends of the bi-directional optical switch; an interference optical signals path (44) coupled to the optical circulator to receive the interference optical signals from the bi-directional switch; and a balanced photo detector (50) to measure a power difference between the interference optical signals and the power reference.

公开(公告)号：EP2455041A3

公开(公告)日：2014-01-08

申请号：EP12152856.6

申请日：2008-11-03

申请人： St. Jude Medical, Inc.

发明人： Alkhatib, Yousef F.

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2418 ,  A61F2002/825 ,  A61F2002/9528 ,  A61F2220/0066 ,  A61F2230/0054 ,  A61F2250/0036

摘要： A frame structure for a collapsible and re-expandable prosthetic heart valve. The frame structure includes an annular annulus portion that is configured for implanting in or near a patient's native heart valve annulus. This annulus portion of the frame structure may include a plurality of annularly spaced Commissure post structures interconnected by connecting structures. The commissure post structures may be more resistant to annular collapse than the connecting structures. In the case of a prosthetic aortic valve, the frame structure may also include an annular aortic portion. The aortic portion may include a plurality of attachment points (for tethers) closest to the annulus portion. Such attachment points and tethers can facilitate re-collapse of a partly deployed valve in the event of a need to reposition or remove the valve.

公开(公告)号：EP2670356A1

公开(公告)日：2013-12-11

申请号：EP12703400.7

申请日：2012-01-31

申请人： St. Jude Medical, Inc.

发明人： KOVACH, Melinda K. ,  CLEGG, Susan E. ,  MORRIS, Benjamin E. ,  FURNISH, Gregory R. ,  BIELEFELD, Eric E. ,  FURNISH, Simon M.

IPC分类号： A61F2/24

CPC分类号： A61F2/2466 ,  A61B5/1076 ,  A61F2/2445 ,  A61F2/2448 ,  A61F2/2496 ,  A61F2250/001 ,  A61F2250/006 ,  A61F2250/0065 ,  A61F2250/0089 ,  A61F2250/0097 ,  B25B15/02 ,  B25B23/142 ,  B25G1/046 ,  B25G3/18

摘要： An adjustable prosthetic anatomical holder system is disclosed. The system is adaptable for use in cardiac surgery and may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size.

公开(公告)号：EP2572675A3

公开(公告)日：2013-09-11

申请号：EP12196437.3

申请日：2008-09-26

申请人： St. Jude Medical, Inc.

发明人： Braido, Peter N. ,  McCarthy, Andrea L. ,  Figueiredo, Rubem L. ,  Neuman, Julia A.

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/89 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/0069

摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

公开(公告)号：EP2572676A3

公开(公告)日：2013-08-21

申请号：EP12196449.8

申请日：2008-09-26

申请人： St. Jude Medical, Inc.

发明人： Braido, Peter N. ,  McCarthy, Andrea L. ,  Figueiredo, Rubem L. ,  Neuman, Julia A.

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/89 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/0069

摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

公开(公告)号：EP2605724A2

公开(公告)日：2013-06-26

申请号：EP11749954.1

申请日：2011-08-17

申请人： St. Jude Medical, Inc.

发明人： KLIMA, Daniel J. ,  WANG, Huisun ,  THOMAS, Ralph J. ,  GEIGER, Gary W.

IPC分类号： A61F2/24

CPC分类号： A61F2/2436 ,  A61B17/00234 ,  A61B2017/00314 ,  A61F2/966 ,  Y10T156/1043

摘要： A delivery system for delivering a collapsible prosthetic heart valve includes a valve support structure for supporting a collapsible prosthetic heart valve, and a distal sheath movable in a longitudinal direction relative to the valve support structure between a first position in which the distal sheath is adapted to surround a collapsible prosthetic heart valve supported on the valve support structure, and a second position in which the distal sheath is adapted to expose the collapsible prosthetic heart valve for deployment. The distal sheath is at least partially formed of an inner polymer layer, an outer polymer layer, and a tubular supporting member sandwiched between the inner polymer layer and the outer polymer layer.

摘要翻译： 用于递送可折叠的假体心脏瓣膜的递送系统包括用于支撑可折叠假体心脏瓣膜的瓣膜支撑结构，以及远端护套，其可在第一位置和第二位置之间移动，所述远端护套可在第一位置和第二位置之间移动， 围绕支撑在所述阀支撑结构上的可折叠假体心脏瓣膜，以及第二位置，其中所述远侧护套适于暴露可折叠的假体心脏瓣膜用于展开。 远侧护套至少部分地由内聚合物层，外聚合物层和夹在内聚合物层和外聚合物层之间的管状支撑构件形成。

公开(公告)号：EP2572675A2

公开(公告)日：2013-03-27

申请号：EP12196437.3

申请日：2008-09-26

申请人： St. Jude Medical, Inc.

发明人： Braido, Peter N. ,  McCarthy, Andrea L. ,  Figueiredo, Rubem L. ,  Neuman, Julia A.

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/89 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/0069

摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

摘要翻译： 人体心脏瓣膜可折叠成较小的圆周尺寸，用于较少侵入性地递送到患者体内，然后在患者的植入部位重新膨胀到工作尺寸，包括可折叠/可扩展的支架状支撑结构和各种部件 的柔性片状材料附着在支撑结构上。 例如，这些片状的其它部件可以包括假体瓣膜小叶，缓冲材料层，箍带材料等。改进的结构和技术被提供用于将这样的其他部件固定到瓣膜的支架状支撑结构。

公开(公告)号：EP2205184B1

公开(公告)日：2012-02-01

申请号：EP08847674.2

申请日：2008-11-03

申请人： St. Jude Medical, Inc.

发明人： ALKHATIB, Yousef F.

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2418 ,  A61F2002/825 ,  A61F2002/9528 ,  A61F2220/0066 ,  A61F2230/0054 ,  A61F2250/0036

摘要： A frame structure for a collapsible and re-expandable prosthetic heart valve. The frame structure includes an annular annulus portion that is configured for implanting in or near a patient's native heart valve annulus. This annulus portion of the frame structure may include a plurality of annularly spaced Commissure post structures interconnected by connecting structures. The commissure post structures may be more resistant to annular collapse than the connecting structures. In the case of a prosthetic aortic valve, the frame structure may also include an annular aortic portion. The aortic portion may include a plurality of attachment points (for tethers) closest to the annulus portion. Such attachment points and tethers can facilitate re-collapse of a partly deployed valve in the event of a need to reposition or remove the valve.