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171.发明公开
公开(公告)号：EP3517126A1
公开(公告)日：2019-07-31
申请号：EP19160307.5
申请日：2016-03-24
发明人： MAHR, Andrea , WEINSCHENK, Toni , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet , SONG, Colette
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：EP3500593A1
公开(公告)日：2019-06-26
申请号：EP17739220.6
申请日：2017-07-04
IPC分类号： C07K14/725 , C07K14/78
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公开(公告)号：EP3463425A1
公开(公告)日：2019-04-10
申请号：EP17727147.5
申请日：2017-05-23
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公开(公告)号：EP3066115B1
公开(公告)日：2019-04-03
申请号：EP14792834.5
申请日：2014-11-03
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175.发明公开
公开(公告)号：EP3394084A1
公开(公告)日：2018-10-31
申请号：EP16802063.4
申请日：2016-11-29
发明人： MAHR, Andrea , WEINSCHENK, Toni , HÖRZER, Helen , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
CPC分类号： A61K39/0011 , A61K35/17 , A61K38/00 , A61K38/1764 , A61K2039/5158 , C07K7/06 , C07K7/08 , C07K14/4748 , C07K14/7051 , C07K16/2833 , C12N15/115 , C12N2310/16
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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176.发明公开
公开(公告)号：EP3359560A1
公开(公告)日：2018-08-15
申请号：EP16774689.0
申请日：2016-09-30
发明人： MAHR, Andrea , WEINSCHENK, Toni , GOLDFINGER, Valentina , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
IPC分类号： C07K14/47 , A61K38/17 , A61K39/00 , G01N33/574 , C07K7/06
CPC分类号： C07K14/4748 , A61K38/1764 , A61K39/0011 , A61K2039/5158 , C07K7/06 , C07K14/7051 , C07K14/70539 , C07K16/2833 , C07K16/30 , C07K2319/40 , C12N5/0636 , C12N15/115 , C12N15/62 , C12N2310/16 , G01N33/57423 , G01N2800/7028
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：EP3042914B1
公开(公告)日：2018-07-04
申请号：EP15193843.8
申请日：2008-07-25
发明人： Singh, Harpreet , Schoor, Oliver , Trautwein, Claudia , Hilf, Norbert , Weinschenk, Toni , Walter, Steffen , Lewandrowski, Peter
CPC分类号： A61K39/0011 , A61K35/17 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/47 , C07K14/4748 , C07K14/495 , C07K14/7051 , C07K16/40 , C07K19/00 , C07K2317/34 , C07K2319/00 , C12N5/0638 , C12N9/0036 , C12N9/13 , C12N2502/1157 , C12Y208/02011
摘要： The present invention relates to amino acid sequences of peptides derived from tumour associated antigens that are able to bind to MHC complexes of either class, and elicit an immune response, as well as to uses of said peptides for the treatment of diseases.
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178.发明公开
公开(公告)号：EP3322717A1
公开(公告)日：2018-05-23
申请号：EP16739102.8
申请日：2016-07-14
IPC分类号： C07K14/47
CPC分类号： A61K35/17 , A61K39/0011 , A61K2039/5158 , C07K7/06 , C07K7/08 , C07K14/4727 , C07K14/4748 , C07K14/7051 , C07K16/30 , C12N15/115 , C12N2310/16 , C12P21/02 , C12Q1/6881 , C12Q1/6886 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57484 , G01N2333/70539 , G01N2500/04
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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179.发明公开NOVEL CELL EPITOPES AND COMBINATION OF CELL EPITOPES FOR USE IN THE IMMUNO-THERAPY OF MYELOMA AND OTHER CANCERS 审中-公开新型细胞表位和细胞表位的组合用于免疫治疗骨髓瘤和其他癌症
公开(公告)号：EP3313860A2
公开(公告)日：2018-05-02
申请号：EP16732263.5
申请日：2016-06-21
发明人： RAMMENSEE, Hans-Georg , STICKEL, Juliane , KOWALEWSKI, Daniel , STEVANOVIC, Stefan , WALZ, Simon
IPC分类号： C07K7/06 , C07K16/00 , G01N33/53 , G01N33/574 , A61K38/00
CPC分类号： C07K7/06 , A61K35/17 , A61K38/00 , A61K39/0011 , A61K2039/5158 , C07K7/08 , C07K14/705 , C07K16/00 , C07K16/30 , C12N5/0636 , C12N2800/00 , G01N33/5308 , G01N33/574
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular myeloma. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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180.发明公开NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST VARIOUS TUMORS 审中-公开新型肽和用于免疫治疗各种肿瘤的肽的组合
公开(公告)号：EP3273986A1
公开(公告)日：2018-01-31
申请号：EP16711659.9
申请日：2016-03-24
发明人： MAHR, Andrea , STEVERMANN, Lea , WEINSCHENK, Toni , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
CPC分类号： C07K14/70539 , A61K38/00 , A61K38/06 , A61K38/08 , A61K38/1774 , A61K39/0005 , A61K39/0011 , A61K45/06 , A61K2039/5158 , A61K2039/54 , A61K2039/57 , A61K2039/572 , A61K2039/585 , C07K7/02 , C07K7/06 , C07K14/001 , C07K14/47 , C07K14/4702 , C07K14/4748 , C07K14/7051 , C07K16/18 , C07K16/2833 , C07K16/30 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2319/00 , C07K2319/40 , C12N5/0636 , C12N5/0638 , C12N9/6491 , C12N2501/998 , C12N2502/11 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , C12Y304/24 , G01N33/505 , G01N33/5088 , G01N33/566 , G01N33/56972 , G01N33/56977 , G01N2333/47 , G01N2333/70503 , G01N2333/7051 , G01N2333/70539 , G01N2500/10
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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