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    IMPROVED MICROBE-BINDING MOLECULES AND USES THEREOF
    15.
    发明公开
    IMPROVED MICROBE-BINDING MOLECULES AND USES THEREOF 审中-公开

    公开(公告)号：EP3763378A1

    公开(公告)日：2021-01-13

    申请号：EP20178742.1

    申请日：2016-08-04

    申请人： President and Fellows of Harvard College

    发明人： WATTERS, Alexander ,  DUSEL, Brendon ,  CARTWRIGHT, Mark ,  SUPER, Michael ,  INGBER, Donald E.

    IPC分类号： A61K38/16 ,  C07K14/78 ,  C07K19/00 ,  G01N33/569 ,  A61K38/00 ,  C07K14/00 ,  C07K14/47

    摘要： Described herein are engineered microbe-targeting molecules, microbe-targeting articles, kits comprising the same, and uses thereof. Such microbe-targeting molecules, microbe-targeting articles, or the kits comprising the same can not only bind or capture of a microbe or microbial matter thereof, but they also have improved capability (e.g., enhanced sensitivity or signal intensity) of detecting a microbe or microbial matter. Thus, the microbe-targeting molecules, microbe-targeting articles, and/or the kit described herein can be used in various applications, e.g., but not limited to assays for detection of a microbe or microbial matter, diagnostic and/or therapeutic agents for diagnosis and/or treatment of an infection caused by microbes in a subject or any environmental surface, and/or devices for removal of a microbe or microbial matter from a fluid.