公开(公告)号：EP3777873A1

公开(公告)日：2021-02-17

申请号：EP20196862.5

申请日：2013-12-24

申请人： Provexis Natural Products Limited

发明人： O'Kennedy, Niamh

IPC分类号： A61K36/81 ,  A23L33/105

摘要： The present invention relates to the use of a fruit extract and optionally other specific nutrients for preventing, reducing or minimising exercise-induced systemic inflammation and/or for promoting recovery from intense exercise. The invention also relates to compositions comprising such fruit extracts.

公开(公告)号：EP3607960A1

公开(公告)日：2020-02-12

申请号：EP19197720.6

申请日：2009-11-02

申请人： Provexis Natural Products Limited

发明人： O'Kennedy, Niamh

IPC分类号： A61K36/81

摘要： Provided are fruit extracts containing glycosylated phenolic acid or a phenolic ester, or derivatives thereof; a glycosylated flavonoid; and a nucleoside. The extracts of the invention are useful as medicaments for the treatment or prevention of a medical condition characterised by inappropriate platelet aggregation. In particular, the medicaments may be of used to maintain heart health by reducing platelet aggregation; benefiting the circulation; and/or normalizing or otherwise benefiting blood flow. Also provided are methods of making an extract of fruit of the Solanaceae family wherein fruit is processed to optimise the platelet aggregation inhibiting activity of the extract.

公开(公告)号：EP3534725A1

公开(公告)日：2019-09-11

申请号：EP17803808.9

申请日：2017-11-02

申请人： Provexis Natural Products Limited

发明人： MUSSLER, Bernd ,  RAEDERSTORFF, Daniel ,  RICHARD, Nathalie

IPC分类号： A23L33/105 ,  A61K36/81

公开(公告)号：EP2349303B1

公开(公告)日：2017-01-11

申请号：EP09756337.3

申请日：2009-11-02

申请人： Provexis Natural Products Limited

发明人： O'KENNEDY, Niamh

IPC分类号： A61K36/81

CPC分类号： A61K36/81 ,  A61K31/7048 ,  A61K31/7064

公开(公告)号：EP2349303A2

公开(公告)日：2011-08-03

申请号：EP09756337.3

申请日：2009-11-02

申请人： Provexis Natural Products Limited

发明人： O'KENNEDY, Niamh

IPC分类号： A61K36/81 ,  A61K31/00

CPC分类号： A61K36/81 ,  A61K31/7048 ,  A61K31/7064

摘要： Provided are methods of making an extract of fruit of the
Solanaceae family wherein fruit is processed to optimise the platelet aggregation inhibiting activity of the extract. The methods involve preparing a start mix of homogenised fruit; separating a water soluble fraction from fruit solids; filtration of the water soluble fraction; and concentration of active agents in the filtration permeate The invention also provides fruit extracts manufactured by such methods, and also fruit extracts containing glycosylated phenolic acid or a phenolic ester, or derivatives thereof; a glycosylated flavonoid; and a nucleoside. The extracts of the invention are useful as medicaments for the treatment or prevention of a medical condition characterised by inappropriate platelet aggregation. In particular, the medicaments may be of use in maintaining heart health by reducing platelet aggregation; benefiting the circulation; and/or normalizing or otherwise benefiting blood flow.

公开(公告)号：EP1848451A2

公开(公告)日：2007-10-31

申请号：EP06709758.4

申请日：2006-02-14

申请人： Provexis Natural Products Limited

发明人： CROSBIE, Lynn ,  O'KENNEDY, Niamh

IPC分类号： A61K36/81

CPC分类号： A61K36/81

摘要： The invention provides the use of a water soluble tomato extract or an active fraction thereof for the manufacture of a medicament for lowering plasma triglyceride levels, the water soluble tomato extract or active fraction thereof being substantially free of lycopene and being substantially free from water-insoluble particulate material. Also provided by the invention is a method of lowering triglyceride levels in the blood of a patient through the administration of the water soluble tomato extracts.