专利检索 ap:("BioNTech AG" OR "Astellas Pharma Inc." OR "TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH") AND inv:"KREUZBERG, Maria" 第 2 页

11.

发明公开
BISPECIFIC TRIVALENT ANTIBODIES BINDING TO CLAUDIN6 OR CLAUDIN18.2 AND CD3 FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES 审中-公开

公开(公告)号：EP3515939A1

公开(公告)日：2019-07-31

申请号：EP17776979.1

申请日：2017-09-20

申请人： Biontech AG , Astellas Pharma Inc.

发明人： SAHIN, Ugur , STADLER, Christiane , FISCHER, Leyla , JENDRETZKI, Arne , TÜRECI, Özlem , LE GALL, Fabrice , KREUZBERG, Maria

IPC分类号： C07K16/28 , A61K39/395 , A61P35/00

12.

发明公开
BISPECIFIC TRIVALENT ANTIBODIES BINDING TO CLAUDIN 6 OR CLAUDIN 18.2 AND CD3 FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES 审中-公开

公开(公告)号：EP4043494A1

公开(公告)日：2022-08-17

申请号：EP22160052.1

申请日：2017-09-20

申请人： BioNTech SE , Astellas Pharma Inc.

发明人： SAHIN, Ugur , STADLER, Christiane , FISCHER, Leyla , JENDRETZKI, Arne , TÜRECI, Özlem , LE GALL, Fabrice , KREUZBERG, Maria

IPC分类号： C07K16/28 , A61K39/395 , A61P35/00

摘要： The present disclosure provides binding agents comprising at least three binding domains, wherein a first binding domain binds to a T cell-specific antigen and a second binding domain and a third binding domain bind to a claudin, and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.