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公开(公告)号:EP1551398A1
公开(公告)日:2005-07-13
申请号:EP03749412.7
申请日:2003-09-05
申请人: Biogen Idec MA Inc.
发明人: LEE, Wen-Cherng , CARTER, Mary, Beth , SUN, Lihong , LYNE, Paul , CHUAQUI, Claudio , ZHENG, Zhongli , SINGH, Juswinder , BORIACK-SJODIN, Paula
IPC分类号: A61K31/415 , A61K31/445
CPC分类号: C07D487/04 , C07D471/04
摘要: Compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I: