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11.发明授权NEW PYRROLIDINE DERIVATIVES AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS 有权新吡咯烷衍生物及其作为乙酰辅酶A羧化酶抑制剂
公开(公告)号：EP2903982B1
公开(公告)日：2016-12-28
申请号：EP13771485.3
申请日：2013-10-02
IPC分类号： C07D403/12 , C07D401/12 , C07D405/04 , C07D405/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04 , C07D207/12 , C07D207/28 , A61K31/41 , A61P3/04 , A61P3/10
CPC分类号： C07D207/12 , C07D207/28 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
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公开(公告)号：EP2997024A1
公开(公告)日：2016-03-23
申请号：EP14723421.5
申请日：2014-05-09
IPC分类号： C07D413/14 , A61K31/41 , C07D403/04 , C07D403/14 , C07D417/14 , C07D207/12 , A61P3/00
CPC分类号： C07D403/04 , C07D207/12 , C07D401/04 , C07D403/14 , C07D413/14 , C07D417/14
摘要： Pyrrolidine derivatives which are inhibitors of acetyl-CoA carboxylase(s) and their use in the treatment of obesity and type-2 diabetes. An exemplary compound is 2-(4-(1-[5-Chloro-6-(2-hydroxy-2-methyl-propoxy)-pyrimidin-4-yl]-(R)-pyrrolidin-3-yloxy)-phenyl)-N-cyclopropyl-propionamide.
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13.发明公开
公开(公告)号：EP2797885A1
公开(公告)日：2014-11-05
申请号：EP12813885.6
申请日：2012-12-28
IPC分类号： C07D205/04 , C07D401/14 , C07D403/14 , C07D407/14 , C07D413/14 , C07D417/14 , A61K31/397 , A61P3/04 , A61P3/10
CPC分类号： C07D205/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D407/14 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The invention relates to new azetidine derivatives of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
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14.发明公开NEW AZETIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 有权新的衍生产品的氮杂环丁烷，PHARMAZEUISCHE组合物及其
公开(公告)号：EP2797884A1
公开(公告)日：2014-11-05
申请号：EP12813379.0
申请日：2012-12-28
IPC分类号： C07D205/04 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D498/04 , A61K31/397 , A61K31/4427
CPC分类号： C07D205/04 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D498/04
摘要： The invention relates to new azetidine derivatives of the formula (I), to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
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公开(公告)号：EP2785690A1
公开(公告)日：2014-10-08
申请号：EP12791809.2
申请日：2012-11-30
IPC分类号： C07D211/22 , C07D211/34 , C07D401/04 , A61K31/445 , A61K31/5377 , A61K31/506 , A61P3/00
CPC分类号： C07D211/34 , C07D211/22 , C07D401/04 , C07D413/14
摘要： The invention relates to new piperidine derivatives of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
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公开(公告)号：EP3601313A1
公开(公告)日：2020-02-05
申请号：EP18710069.8
申请日：2018-03-16
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公开(公告)号：EP2948442B1
公开(公告)日：2016-10-26
申请号：EP14701328.8
申请日：2014-01-20
IPC分类号： C07D405/14 , C07D413/14 , C07D401/14 , C07D401/04 , C07D417/14
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14
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18.发明授权NEW AZETIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 有权新的衍生产品的氮杂环丁烷，PHARMAZEUISCHE组合物及其
公开(公告)号：EP2797884B1
公开(公告)日：2016-04-13
申请号：EP12813379.0
申请日：2012-12-28
IPC分类号： C07D205/04 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D498/04 , A61K31/397 , A61K31/4427
CPC分类号： C07D205/04 , C07D401/04 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D498/04
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19.发明授权
公开(公告)号：EP2794587B1
公开(公告)日：2016-03-16
申请号：EP12812983.0
申请日：2012-12-21
IPC分类号： C07D401/04 , C07D413/12 , C07D417/12 , C07D211/26 , A61K31/451 , A61K31/454 , A61K31/4545 , A61P3/00
CPC分类号： C07D211/26 , C07D401/04 , C07D413/12 , C07D417/12
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20.发明公开PYRIMIDINE-SUBSTITUTED PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 有权PYRIMIDINSUBSTITUIERTE吡咯烷，其组合物及其用途制药
公开(公告)号：EP2986604A1
公开(公告)日：2016-02-24
申请号：EP14716333.1
申请日：2014-04-10
IPC分类号： C07D405/14 , C07D413/14 , C07D491/08 , C07D403/04 , C07D403/14 , C07D417/14 , C07D491/04 , C07D498/04 , A61P3/00 , A61K31/506 , A61K31/5377 , A61K31/5386
CPC分类号： C07D417/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D413/14 , C07D491/04 , C07D491/08 , C07D498/04
摘要： The invention relates to new pyrrolidine derivatives of the formula (I), wherein R
1 to R
3 , Ar, L T and n are as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
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