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公开(公告)号：EP3427696A1
公开(公告)日：2019-01-16
申请号：EP18186664.1
申请日：2013-03-01
发明人： MATHENY, Robert G.
IPC分类号： A61F2/24
摘要： Anchored cardiovascular valves (40) having a support member (10) of remodelable decellularized ECM material with at least one leaflet (30) formed therein that is sized and configured to selectively restrict regurgitating blood through the valve (11, 40, 50, 60, 70), and at least one anchoring mechanism (20A, 20B, 42A, 42B, 52A, 52B, 62A, 62, 65, 67). In a preferred embodiment of the invention, the anchored valves (50) have two anchoring mechanisms (20A, 42A, 52A, 62A), i.e. proximal and distal anchoring mechanisms (20A, 42A, 52A, 62A).
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公开(公告)号：EP2797556B1
公开(公告)日：2018-08-01
申请号：EP13861484.7
申请日：2013-03-01
发明人： MATHENY, Robert G.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2436 , A61F2220/0016 , A61F2230/0095
摘要： Anchored cardiovascular valves having a support member with at least one leaflet formed therein that is sized and configured to selectively restrict regurgitating blood through the valve, and at least one anchoring mechanism. In a preferred embodiment of the invention, the anchored valves have two anchoring mechanisms, i.e. proximal and distal anchoring mechanisms
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公开(公告)号：EP3229732A1
公开(公告)日：2017-10-18
申请号：EP15866643.8
申请日：2015-12-03
发明人： MATHENY, Robert G.
CPC分类号： A61F2/06 , A61K35/12 , A61K38/18 , A61L27/34 , A61L27/3633 , A61L27/507 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2400/16
摘要： Vascular grafts for treating, reconstructing and replacing damaged or diseased cardiovascular vessels that are formed from decellularized extracellular matrix (ECM). The vascular grafts include outer or outer and inner coatings that provide structural reinforcement.
摘要翻译： 用于治疗，重建和替代由脱细胞胞外基质（ECM）形成的受损或患病心血管血管的血管移植物。 血管移植物包括提供结构增强的外部或外部和内部涂层。
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公开(公告)号：EP2991599A1
公开(公告)日：2016-03-09
申请号：EP14791394.1
申请日：2014-04-29
发明人： MATHENY, Robert G. , COX, James , FALLON, Anna
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2457 , A61F2230/0065 , A61F2230/0069 , A61F2250/0067
摘要： A valve mounting apparatus having an elongated tubular mesh structure with proximal and distal ends, a cardiovascular structure engagement region disposed between the proximal and distal ends, and a lumen therethrough, the distal end of the structure including a valve engagement region that is configured to engage a first end of a prosthetic valve, the mesh structure being configured to transition from a pre-deployment configuration, wherein the structure is capable of being disposed at a cardiovascular valve region, such as a valve annulus region, to a post-deployment expanded configuration, wherein the cardiovascular structure engagement region is anchored to the cardiovascular valve region.
摘要翻译： 1.一种瓣膜安装装置，其具有带近端和远端的细长管状网状结构，设置在近端和远端之间的心血管结构接合区域以及穿过其中的内腔，所述结构的远端包括阀接合区域，所述阀接合区域被构造成接合 假体瓣膜的第一端，所述网状结构构造成从预展开构型过渡到所述展开后构型，其中所述结构能够设置在心血管瓣膜区域诸如瓣膜瓣环区域， 其中，所述心血管结构接合区域锚定到所述心血管瓣膜区域。
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15.发明公开PROSTHETIC TISSUE VALVES AND METHODS FOR ANCHORING SAME TO CARDIOVASCULAR STRUCTURES 审中-公开假体组织瓣膜和将其固定到心血管结构的方法
公开(公告)号：EP2991588A1
公开(公告)日：2016-03-09
申请号：EP14791609.2
申请日：2014-03-29
发明人： MATHENY, Robert G.
IPC分类号： A61F2/24
CPC分类号： A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2457 , A61F2210/0004 , A61F2210/0057 , A61F2220/0075 , A61F2230/0006 , A61F2230/0023 , A61F2230/0069 , A61F2250/0036 , A61F2250/0067
摘要： A prosthetic atrioventricular tissue valve comprising a continuous tubular member formed from a first biocompatible material, the tubular member having proximal and distal ends, and at least one valve leaflet fomied therein, the distal end of the tubular member including cardiovascular structure engagement means for connecting the tubular member to a cardiovascular structure, the cardiovascular structure engagement means comprising a plurality of elongated members that extend distally from the distal end of the tubular member.
摘要翻译： 一种假体性房室组织瓣膜，其包括由第一生物相容性材料形成的连续管状部件，所述管状部件具有近端和远端以及至少一个瓣膜小叶，其中形成有至少一个瓣叶，所述管状部件的远端包括心血管结构接合装置， 所述心血管结构接合装置包括从所述管状构件的所述远端向远侧延伸的多个细长构件。
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