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公开(公告)号：EP1025241B1
公开(公告)日：2005-03-30
申请号：EP98956181.6
申请日：1998-10-23
发明人： SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , POULOSE, Ayrookaran, J. , COLLIER, Katherine, D. , CALDWELL, Robert, M. , BAECK, André, C.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
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12.发明公开
公开(公告)号：EP2705145A2
公开(公告)日：2014-03-12
申请号：EP12722015.0
申请日：2012-05-04
发明人： SOUTER, Philip, Frank , MAGENNIS, Euan, John , WARD, Glenn, Steven , AMIN, Neelam, S. , AUGUSTYN, Katherine , BASLER, Joshua, R. , CASCÃO-PEREIRA, Luis, Gustavo , COLLIER, Katherine, D. , CONCAR, Edward, M. , ESTELL, David, A. , KELLIS, James, T., Jr. , PISARCHIK, Alexander , POULOSE, Ayrookaran, Joseph , YAO, Jian
CPC分类号： C11D3/38618 , C11D3/38609
摘要： The present invention provides consumer products comprising a serine protease variant, more specifically subtilisin variants produced there from. Specifically, the present invention provides consumer products comprising a serine protease variant, more specifically a subtilisin variant having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides methods of making such compositions and methods of treating surfaces, particularly fabric surfaces comprising contacting a surface with an aqueous liquor comprising a serine protease variant, more specifically subtilisin variants and an adjunct material.
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公开(公告)号：EP1025241B2
公开(公告)日：2009-10-21
申请号：EP98956181.6
申请日：1998-10-23
发明人： SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , POULOSE, Ayrookaran, J. , COLLIER, Katherine, D. , CALDWELL, Robert, M. , BAECK, André, C.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue corresponds to position 103 in combination with one or more of the following substitutions at residue positions corresponding to positions 1, 3, 4, 8, 10, 12, 13, 15, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274, and 275 of Bacillus amyloliquefaciens subtilisin, wherein when a substitution at a position corresponding to residue position 103 is combined with a substitution at a position corresponding to residue position 76, there is also a substitution at one or more residue positions other than residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin.
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公开(公告)号：EP1025241A2
公开(公告)日：2000-08-09
申请号：EP98956181.6
申请日：1998-10-23
发明人： SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , POULOSE, Ayrookaran, J. , COLLIER, Katherine, D. , CALDWELL, Robert, M. , BAECK, André, C.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue corresponds to position 103 in combination with one or more of the following substitutions at residue positions corresponding to positions 1, 3, 4, 8, 10, 12, 13, 15, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274, and 275 of Bacillus amyloliquefaciens subtilisin, wherein when a substitution at a position corresponding to residue position 103 is combined with a substitution at a position corresponding to residue position 76, there is also a substitution at one or more residue positions other than residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin.
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公开(公告)号：EP2344531B1
公开(公告)日：2014-12-10
申请号：EP08876414.7
申请日：2008-10-15
申请人： Danisco US Inc.
发明人： AMIN, Neelam, S. , COLLIER, Katherine, D. , ESTABROOK, Melodie , ESTELL, David, A. , FOX, Bryan , POWER, Scott, D. , SCHMIDT, Brian, F. , VOGTENTANZ, Gudrun
IPC分类号： A61K8/64 , C12N1/21 , A61K38/55 , A61P17/00 , A61P17/06 , A61P17/14 , A61Q19/00 , A61Q7/00 , C07K14/81 , C12N15/62
CPC分类号： C12N15/62 , C07K14/811
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公开(公告)号：EP2344531A1
公开(公告)日：2011-07-20
申请号：EP08876414.7
申请日：2008-10-15
申请人： Danisco US Inc.
发明人： AMIN, Neelam, S. , COLLIER, Katherine, D. , ESTABROOK, Melodie , ESTELL, David, A. , FOX, Bryan , POWER, Scott, D. , SCHMIDT, Brian, F. , VOGTENTANZ, Gudrun
CPC分类号： C12N15/62 , C07K14/811
摘要： The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
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17.发明公开SURFACTANTS THAT IMPROVE THE CLEANING OF LIPID-BASED STAINS TREATED WITH LIPASES 审中-公开TENSIDE ZUR VERBESSERTEN REINIGUNG VON MIT LIPASEN BEHANDELTEN FLECKEN AUF FETTBASIS
公开(公告)号：EP2516606A1
公开(公告)日：2012-10-31
申请号：EP10787655.9
申请日：2010-12-02
申请人： Danisco US Inc.
CPC分类号： C11D3/38627 , C11D1/62 , C11D1/662 , C11D1/75 , C11D1/92 , C11D3/221 , C12N9/20 , C12Y301/01003
摘要： Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in, e.g., laundry cleaning and dishwashing.
摘要翻译： 描述了与使用脂肪酶与所选择的表面活性剂组合以介导由脂肪酶产生的脂肪酸的释放从织物和其它表面除去油性污渍的组合物和方法。 组合物和方法可用于例如洗衣清洁和洗碗。
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公开(公告)号：EP3470504A8
公开(公告)日：2019-06-05
申请号：EP18211035.3
申请日：2010-12-02
申请人： Danisco US Inc.
摘要： Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in e.g. laundry cleaning and dishwashing
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公开(公告)号：EP3470504A1
公开(公告)日：2019-04-17
申请号：EP18211035.3
申请日：2010-12-02
申请人： Danisco US Inc.
摘要： Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in e.g. laundry cleaning and dishwashing
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