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16 条记录 (耗时 0.014 秒)

    Hemostatic compositions and devices
    12.
    发明公开
    Hemostatic compositions and devices 有权
    Blutstillende Zusammensetzung und Vorrichtung

    公开(公告)号：EP1632252A1

    公开(公告)日：2006-03-08

    申请号：EP05254033.3

    申请日：2005-06-28

    申请人： ETHICON, INC.

    发明人： Looney, Dwayne L. ,  Zhang, Guanghui ,  Martins, Sonia

    IPC分类号： A61L15/00 ,  A61L15/22 ,  A61F13/00 ,  A61L24/00

    CPC分类号： A61L24/104 ,  A61L24/0036 ,  A61L24/102

    摘要： The present inventions includes a plurality of packed particles that contain interstitial pores, where the interstitial pores have a pore volume and a median pore diameter effective to provide improved absorption of physiological fluids or an aqueous media when placed in contact therewith, compared to a plurality of unpacked particles of the same material, where the particles are made of a biocompatible material and hemostatic agents and have an average diameter suitable for use in providing hemostasis to a site of a body of a mammal requiring hemostasis, hemostatic compositions containing such plurality of packed particles, methods of making such particles and compositions and medical devices suitable for delivering and containing the hemostatic plurality of particles and/or composition to a site of a body.

    摘要翻译： 本发明包括多个包含间质孔的填充颗粒，其中间隙孔具有孔容积和中值孔径，其有效地提供改善的生理流体吸收或与其接触时的水性介质，与多个 相同材料的未包装的颗粒，其中颗粒由生物相容性材料和止血剂制成，并且具有适合用于向要求止血的哺乳动物的身体部位提供止血的平均直径，含有这种多个包装颗粒的止血组合物 制备这样的颗粒和组合物的方法以及适于将止血多个颗粒和/或组合物递送并包含到身体部位的医疗装置。

    Hemostatic wound dressings and methods of making same
    14.
    发明公开
    Hemostatic wound dressings and methods of making same 审中-公开
    HämostatischerWundverbang und Verfahren zu seiner Herstellung

    公开(公告)号：EP1462123A1

    公开(公告)日：2004-09-29

    申请号：EP03254107.0

    申请日：2003-06-27

    申请人： Ethicon, Inc.

    发明人： Looney, Dwayne Lee ,  Crilley, John ,  Guo, Jian Xin ,  Zhang, Guanghui ,  Pendharkar, Sanyog Manohar

    IPC分类号： A61L15/28 ,  A61L15/32 ,  A61L15/44 ,  A61L15/64

    CPC分类号： A61L15/425 ,  A61L15/28 ,  A61L2400/04

    摘要： The present invention is directed to methods of making wound dressings that include the steps of providing a solution of a water-soluble or water-swellable biocompatible polymer dissolved in a solvent for the polymer, providing a fabric substrate having a first surface and a second surface opposing the first surface, the fabric having properties effective for use as a hemostat and containing fibers prepared from a biocompatible polymer, contacting the fabric substrate with the polymer solution under conditions effective to distribute the polymer solution substantially homogenously on the first and second surfaces and through the fabric substrate, transferring the fabric substrate having the polymer solution substantially homogenously distributed there through to a lyophilization unit under conditions effective to maintain the homogeneous distribution on and throughout the substrate, and lyophilizing the fabric having the polymer solution distributed there through, thereby providing a porous, polymeric matrix substantially homogeneously distributed on the first and second surfaces and through the fabric, the matrix being made-up of the lyophilized water-soluble or water-swellable polymer.

    摘要翻译： 本发明涉及制造伤口敷料的方法，其包括以下步骤：提供溶解在聚合物的溶剂中的水溶性或水溶胀性生物相容性聚合物的溶液，提供具有第一表面和第二表面的织物基材 与第一表面相对，织物具有有效用作止血剂的性质并且含有由生物相容性聚合物制备的纤维，在有效地将聚合物溶液基本均匀地分布在第一和第二表面上并通过 织物基底，将具有聚合物溶液的织物基底基本上均匀地分布在此处，在有效保持基底上和整个基底上均匀分布的条件下冻干，并且将具有聚合物溶液的织物冻干，从而提供ap 基本均匀地分布在第一和第二表面上并通过织物的基质由冻干的水溶性或水可溶胀聚合物组成。

    Hemostatic wound dessings containing proteinaceous polymers
    16.
    发明公开
    Hemostatic wound dessings containing proteinaceous polymers 审中-公开
    含蛋白质聚合物的止血伤口处理

    公开(公告)号：EP1535631A2

    公开(公告)日：2005-06-01

    申请号：EP04257230.5

    申请日：2004-11-22

    申请人： ETHICON, INC.

    发明人： Looney, Dwayne Lee ,  Zhang, Guanghui

    IPC分类号： A61L15/32 ,  A61L15/42

    CPC分类号： A61L15/425 ,  A61L15/28 ,  A61L15/32 ,  A61L15/64 ,  A61L27/20 ,  A61L2400/04 ,  C08L1/04 ,  C08L1/16 ,  C08L1/284 ,  C08L5/08 ,  D04B21/16 ,  D10B2509/022 ,  D10B2509/08 ,  Y10T442/2525 ,  C08L1/24 ,  C08L5/00 ,  C08L1/02 ,  C08L2666/26

    摘要： The present invention is directed to a hemostatic wound dressing that utilizes a fibrous, fabric substrate made from a biocompatible polymer suitable for use in the body and containing a first surface and a second surface opposing the first surface, the fabric having flexibility, strength and porosity effective for use as a hemostat; and further having a porous, polymeric matrix distributed on the first and second surfaces and through the fabric substrate, the porous, polymeric matrix being made of a biocompatible, water-soluble or water-swellable proteinaceous polymer.

    摘要翻译： 本发明涉及一种止血伤口敷料，其利用由适合用于身体并且包含第一表面和与第一表面相对的第二表面的生物相容性聚合物制成的纤维织物基底，所述织物具有柔韧性，强度和孔隙率 有效用作止血剂; 并且还具有分布在第一和第二表面上并穿过织物基底的多孔聚合物基质，多孔聚合物基质由生物相容性，水溶性或水溶胀性蛋白质聚合物制成。